Prevent decrease on bone mass after tooth extraction and increase bone mass
| Project/Area Number |
15K15750
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 抜歯 / 歯槽骨 / サンゴ / 骨増生 / CAD/CAM / 再生 / 生体吸収性 / 組織親和性 / 新生骨 / 足場材料 |
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| Outline of Final Research Achievements |
In cases where teeth are lost, maintenance of the denture and adaptation of the implant becomes difficult because the bone mass of the jaw decreases. Therefore, as a treatment after tooth extraction aiming at preventing reduction of bone mass, and also to increase bone mass, we investigated the effects of compression hemostasis by gauze after extraction and coral filling material implantation on bone. Immediately after removing the left molar of the mandibular bone of the Beagle dog, it was compressed by gauze, coral implantation was used as an experimental group, and right molar that was not pressed was used as a control. After implantation, the mandible was removed. Mandibular bone was measured bone density with X-ray and histological observation of new bone formation by confocal laser scanning microscope. Although there was no effect of compression by gauze on bone mass on this time, using bone filling agent by coral had the effect of bone augmentation.
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Report
(4 results)
Research Products
(12 results)
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[Journal Article] Effects of <i>Montipora digitata</i> Exoskeleton- derived Aragonite Particles on Human Fibroblasts for Cell Proliferation and Collagen Production <i>in Vitro</i>2017
Author(s)
Okamura T, Takeuchi T, Honda S, Tominaga K, Naruse K, Morita S, Imai K, Masuno K, Ono Y, Nishikawa T, Tanaka A
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Journal Title
Journal of Oral Tissue Engineering
Volume: 15
Issue: 1
Pages: 41-48
DOI
NAID
ISSN
1348-9623, 1880-0823
Related Report
Peer Reviewed / Open Access
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[Journal Article] <i>Montipora digitata</i> Exoskeleton Derived Aragonite Particles are useful Scaffold for Tissue-engineered Vascular Graft <i>in Vitro</i>2017
Author(s)
Okamura T, Uemura N, Baba S, Yasuda N, Yamashiro H, Imai K, Nishikawa T, Shimizu H, Shida M, Tominaga K, Tanaka A
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Journal Title
Nano Biomedicine
Volume: 9
Issue: 2
Pages: 105-111
DOI
NAID
ISSN
1883-5198, 2185-4734
Related Report
Peer Reviewed / Open Access
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[Journal Article] Comparative Study of Physical and Morphological Characteristics odf Cultured and Natural Coral as a Bone Augmentation Scaffold.2016
Author(s)
Nishikawa T, Okamura T, Masuno K, Matsumoto H, Hirose M, Uemura N, Yasuda N, Hidaka M, Baba S, Imai K, Tanaka A.
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Journal Title
J Oral Tissue Engin.
Volume: 14
Pages: 107-113
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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