Mathematical and computational modelling of the effects of facial aging using skin viscoelasticity and three-dimensional facial topography

• Project/Area Number: 15K15755
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Orthodontics/Pediatric dentistry
• Research Institution: Osaka University
• Principal Investigator: Takada Kenji 大阪大学, 国際医工情報センター, 招へい教授 (50127247)
• Co-Investigator(Kenkyū-buntansha): 谷川 千尋 大阪大学, 歯学部附属病院, 講師 (70423142)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 三次元 / 加齢 / 顔 / 粘弾性 / 数理モデル / 予測

Outline of Final Research Achievements

In orthodontic treatments, developing a mathematical model to predict the effects of facial aging using skin viscoelasticity and three-dimensional facial topography leads to effective treatment planning that reflects facial aging. Thus, the present study aimed: (1) to analyze the three-dimensional facial soft-tissue topography and skin viscoelasticity at rest and during facial expressions in two age groups (young adult and elderly groups), (2) to clarify the vector elements (or mathematical expressions) that can effectively detect facial aging, and (3) to develop a mathematical model to predict the effects of facial aging using the aforementioned vector elements.

Research Products

• [Journal Article] Efficacy of maxillary anterior segmental distraction osteogenesis in patients with cleft lip and palate (2018)
  • Author(s): Tanikawa C, Hirata K, Aikawa T, Maeda J, Kogo M, Iida S, Yamashiro T
  • Journal Title: Cleft Palate Craniofac J Volume: in press Issue: 10 Pages: 1375-1381
  • DOI: 10.1177/1055665618758692
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Test-retest reliability of smile tasks using three-dimensional facial topography (2018)
  • Author(s): Tanikawa C, Takada K:
  • Journal Title: Angle Orthod Volume: in press Issue: 3 Pages: 319-328
  • DOI: 10.2319/062617-425.1
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Electrophysiological and Morphological Properties of α and γ Motoneurons in the Rat Trigeminal Motor Nucleus (2018)
  • Author(s): Nishimura K, Ohta M, Saito M, et al.
  • Journal Title: Frontiers in Cellular Neuroscience Volume: 12 Pages: 9-9
  • DOI: 10.3389/fncel.2018.00009
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A novel method to detect 3D mandibular changes related to soft-diet feeding (2017)
  • Author(s): Kana Kono, Chihiro Tanikawa, Takeshi Yanagita, Hiroshi Kamioka, and Takashi Yamashiro
  • Journal Title: Frontiers in Physiology Volume: ー
  • DOI: 10.3389/fphys.2017.00567
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] mprovement in three-dimensional facial configuration and jaw motion following surgical orthodontic treatment of a case with jaw deviation (2017)
  • Author(s): Takigawa Y, Tanikawa C, Yashiro K, Takada K
  • Journal Title: Orthod Waves Volume: 76(3) Issue: 3 Pages: 184-196
  • DOI: 10.1016/j.odw.2017.04.001
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] A distinct functional distribution of α and γ motoneurons in the rat trigeminal motor nucleus. (2017)
  • Author(s): Morita-Isogai, Y., Sato, H., Saito, M., Kuramoto, E., Yin, D., Kaneko, T., Yamashiro, T., Takada, K., Oh, S.B., Toyoda, H., & Kang, Y.
  • Journal Title: Brain Structure and Function Volume: - Issue: 7 Pages: 1-9
  • DOI: 10.1007/s00429-017-1400-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] Hemodynamic changes in the perioral muscles before and after exercise load A discussion of the methodology (2017)
  • Author(s): Okamoto K, Tanikawa C, Tsuno K, Nakamura H, Kashiwada H, Takata S, Karino M, Takada K
  • Organizer: nternational Cleft Congress 2017
  • Int'l Joint Research
• [Presentation] Effects of Maxillary Anterior Segmental Distraction Osteogenesis in Patients with a Cleft Lip and Palate (2017)
  • Author(s): Tanikawa C, Hirata K, Aikawa T, Yamashiro T
  • Organizer: International Cleft Congress 2017
  • Int'l Joint Research
• [Presentation] Changes in Facial Morphology after Presurgical Nasoalveolar Molding in Patients with Unilateral Cleft Lip and Palat (2017)
  • Author(s): Matsukawa M, Tanikawa C, Yamashiro T, Kogo M.
  • Organizer: nternational Cleft Congress 2017
  • Int'l Joint Research
• [Presentation] ３次元画像解析の基礎と矯正歯科治療への応用 (2017)
  • Author(s): 谷川千尋
  • Organizer: 第76回日本矯正歯科学会学術大会
  • Invited
• [Presentation] 片側性口唇口蓋裂を有する患者において口蓋裂手術法が矯正歯科治療法に与える影響 (2017)
  • Author(s): 谷川千尋、岡 綾香、黒坂 寛、西村佳世、山城 隆
  • Organizer: 第41回日本口蓋裂学会総会・学術大会
• [Presentation] 症候群頭蓋縫合早期癒合症を有する患者における軟・硬組織の三次元評価手法の確立 (2017)
  • Author(s): 谷川千尋、月星陽介、Lee Dong Hoon、山城 隆
  • Organizer: 第41回日本口蓋裂学会総会・学術大会
• [Presentation] 大阪大学歯学部附属歯科技工士学校におけるデジタルデンティストリーおよび三次元プリンター実習の満足度調査 (2017)
  • Author(s): 谷川千尋、岡 綾香、町 博之、野崎一徳、中本将嗣、山城 隆
  • Organizer: 第59回近畿東海矯正歯科学会学術大会
• [Presentation] 顎前突を伴うAarskog-Scott 症候群の一症例 (2017)
  • Author(s): 中津川昴平、谷川千尋、岡 綾香、山城 隆
  • Organizer: 第59回近畿東海矯正歯科学会学術大会
• [Presentation] 上下顎の空隙歯列および前歯部開咬を伴うCoffin-Lowry 症候群の一症例 (2017)
  • Author(s): 虫明 仁、岡 綾香、谷川千尋、山城 隆
  • Organizer: 第59回近畿東海矯正歯科学会学術大会
• [Presentation] エッジワイズ装置装着患者における口腔衛生指導の効果について (2017)
  • Author(s): 瀧本真弥、谷川千尋、磯貝由佳子、山城 隆
  • Organizer: 第59回近畿東海矯正歯科学会学術大会
• [Presentation] BiPAP 使用に起因した上顎骨の劣成長が疑われる先天性中枢性肺胞低換気症候群の一治験例 (2017)
  • Author(s): 森田知里、谷川千尋、上村 夢、山城 隆
  • Organizer: 第59回近畿東海矯正歯科学会学術大会
• [Presentation] 顔面皮膚の粘弾性・色彩・水分量の加齢変化 (2017)
  • Author(s): 谷川千尋、岡本圭子、築野喜和子、中村裕行、柏田紘明、高田定樹、黒田嘉宏、大城理、和田成生、高田健治
  • Organizer: 第22回日本顔学会大会
• [Presentation] 矯正歯科治療要否を判定するartificial intelligence(AI) システム (2017)
  • Author(s): 谷川千尋、石垣光昴、LEE Chonho、竹内優斗、清水優仁、野崎一徳、山城 隆
  • Organizer: 第76回日本矯正歯科学会学術大会
• [Presentation] 食餌性状がマウス上顎骨の三次元形態に及ぼす影響 (2017)
  • Author(s): 河野加奈、谷川千尋、柳田剛志、上岡 寛、山城 隆
  • Organizer: 第76回日本矯正歯科学会学術大会
• [Presentation] Artificial intelligence (AI)を用いた矯正歯科治療における顔画像特徴記述文生成の試み (2017)
  • Author(s): 谷川千尋、石垣光昴、LEE Chonho、竹内優斗、清水優仁、野崎一徳、山城
  • Organizer: 第76回日本矯正歯科学会学術大会
• [Presentation] 咬筋および口唇に運動負荷を加えた場合の血流動態の変化 (2017)
  • Author(s): 岡本圭子、谷川千尋、中村裕行、高田定樹、高田健治
  • Organizer: 第76回日本矯正歯科学会学術大会
• [Presentation] 異なる年齢群における顔面皮膚の粘弾性・色彩の違いについて (2017)
  • Author(s): 谷川千尋、岡本圭子、中村裕行、高田定樹、高田健治
  • Organizer: 第76回日本矯正歯科学会学術大会
• [Presentation] Reproducibility of Smiling Efforts Using 3D Facial Topograph (2016)
  • Author(s): Dr. Chihiro Tanikawa PhD, and Kenji Takada
  • Organizer: The International Association for Dental Research (IADR)
  • Place of Presentation: Seoul, Republic of Korea（ソウル、韓国）
  • Year and Date: 2016-06-22
  • Int'l Joint Research
• [Presentation] 顔の皮膚および皮下組織の物理性状と血流動態の加齢によるへんか：方法論の検討 (2016)
  • Author(s): 築野喜和子、谷川千尋、岡本圭子、中村裕行、柏田紘明、高田定樹、高田健治
  • Organizer: 第16回日本抗加齢医学会総会
  • Place of Presentation: パシフィコ横浜（横浜市、日本）
  • Year and Date: 2016-06-10
• [Presentation] 顔の皮膚および皮下組織の物理性状と血流動態の加齢による変化：方法論の検討 (2016)
  • Author(s): ・築野喜和子、谷川千尋、岡本圭子、中村裕行、柏田紘明、高田定樹、高田健治第
  • Organizer: 16回日本抗加齢医学会総会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2016-06-10