| Project/Area Number |
15K15778
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
MAEDA NOBUKO 鶴見大学, 歯学部, 教授 (10148067)
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| Research Collaborator |
YAMAMOTO Tomoo
KIMURA Yosuke
WATANABE Hitoshi
HARADA Raitaro
YOKOTA Ayako
KOZEKI Shoko
KUSASHIO Eiji
|
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | アムホテリシンB / カンジダ / 歯垢 / 口腔清掃 / 粘膜症状 / 口腔ケア / 介護老人施設 / QOL / 口腔内環境 / 常在真菌 / 歯垢付着量 / 口腔カンジダ症 / 経管栄養 / 胃婁 |
|---|
| Outline of Final Research Achievements |
A healthy oral environment should be maintained to promote gastrointestinal and general conditions. However, various microorganisms rapidly grow in the oral cavity, requiring sufficient oral care. Daily oral care is often difficult. We investigated how fungi, such as Candida, can be suppressed with antifungal medicines for appropriate management and maintenance of the oral environment. As a result, the continued use of antifungal medicines reduced fungi in the oral cavity and improved oral cleaning conditions and mucosal symptoms, promoting a healthy oral environment. In addition, it improved bowel movements with satisfactory body weight control, supporting its effects on general health maintenance.
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