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Study on cerebellar information processing underlying flexible motor control and learning

Research Project

Project/Area Number 15K16086
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Life / Health / Medical informatics
Research InstitutionChubu University

Principal Investigator

INAGAKI Keiichiro  中部大学, 工学部, 講師 (10568942)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords眼球運動 / 前庭系 / 小脳 / 運動学習 / 大規模シミュレーション / 前庭動眼反射 / モデルシミュレーション / 前庭 / モデルんシミュレーション / 空間定位 / 自己運動感覚
Outline of Final Research Achievements

The vestibule-ocular reflex (VOR) has been one of the most popular model systems to investigate the role of the cerebellum in adaptive motor control. It was reported that performance of the VOR is modifiable context-dependently. Namely, VOR gain can be increased for leftward head rotation, while it can be decreased for rightward head rotation simultaneously. This instance implies the possibility that the cerebellum flexibly processes context dependent input signals. Presently, we conducted a simulation study on context-dependent VOR motor learning, especially in head direction selective motor learning, using the artificial cerebellar neuronal network model that we developed to understand the origin of the flexible cerebellar motor learning.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (16 results)

All 2017 2016 2015

All Journal Article (6 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 6 results) Presentation (10 results) (of which Int'l Joint Research: 5 results)

  • [Journal Article] Computational theory underlying acute vestibulo-ocular reflex motor learning with cerebellar long-term depression and long-term potentiation2017

    • Author(s)
      K. Inagaki, Y. Hirata
    • Journal Title

      The Cerebellum

      Volume: vol.17 Issue: 4 Pages: 1-13

    • DOI

      10.1007/s12311-017-0857-6

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Bilateral cerebellar spiking neural network model to simulate motor learning of the vetibuloocular reflex2016

    • Author(s)
      K. Inagaki, Y. Hirata
    • Journal Title

      Lecture Notes in Computer Science

      Volume: vol. 9950 Pages: 252-258

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 小脳両半球構造を陽に記述した人工小脳による前庭動眼反射運動学習シミュレーション2016

    • Author(s)
      稲垣圭一郎,平田豊
    • Journal Title

      電子情報通信学会技術研究報告

      Volume: vol.116 Pages: 85-90

    • Related Report
      2016 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] 並進・傾き運動識別の曖昧性を解決する小脳神経回路モデル2016

    • Author(s)
      飯田祥貴,稲垣圭一郎,平田 豊
    • Journal Title

      電子情報通信学会技術研究報告

      Volume: vol.115, no514 Pages: 155-160

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] 眼球運動神経積分器を構成する両側性神経回路における同側フィードバックと対側抑制機構の役割評価2015

    • Author(s)
      稲垣圭一郎,平田豊
    • Journal Title

      電子情報通信学会技術研究報告

      Volume: vol.115, no.111 Pages: 63-68

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Different roles for ipsilateral positive feedback and commissural inhibitory networks in oculomotor velocity to position neural integration2015

    • Author(s)
      K Inagaki, Y Hirata
    • Journal Title

      BMC Neuroscience

      Volume: 16 Issue: S1 Pages: 100-100

    • DOI

      10.1186/1471-2202-16-s1-p100

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Presentation] Evaluation of roles of cerebellar Golgi and basket/stellate cells in the vestibuloocular reflex motor learning: a computational study2016

    • Author(s)
      K. Inagaki, Yutaka Hirata
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      San Diego, US
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 小脳両半球構造を陽に記述した人工小脳による前庭動眼反射運動学習シミュレーション2016

    • Author(s)
      稲垣圭一郎,平田 豊
    • Organizer
      ヒューマン情報処理研究会
    • Place of Presentation
      奈良春日野国際フォーラム(奈良市、奈良県)
    • Year and Date
      2016-09-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] Cerebellar neural network model for resolving tilt-translation ambiguity2016

    • Author(s)
      K. Inagaki, Y. Iida, T. Yakusheva, P.M. Blazquez, Y. Hirata
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県、横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 小脳における並進運動と傾き運動の識別メカニズムの考察2016

    • Author(s)
      稲垣圭一郎,飯田祥貴,平田 豊
    • Organizer
      人工知能学会全国大会
    • Place of Presentation
      北九州国際会議場(福岡県、北九州市)
    • Year and Date
      2016-06-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 並進・傾き運動識別の曖昧性を解決する小脳神経回路モデル2016

    • Author(s)
      飯田祥貴,稲垣圭一郎,平田 豊
    • Organizer
      ニューロコンピューティング研究会
    • Place of Presentation
      玉川大学
    • Year and Date
      2016-03-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Development of an on-line simulation platform for neuroscience research, 8th INCF Congress of Neuroinformatics2015

    • Author(s)
      H. Ikeno, T. Yamazaki, Y. Kamiyama, A. Ishihara, K. Inagaki, Y. Hirata, Y. Okumura, T. Kannon, S. Satoh, H. Wagatsuma, Y. Asai, Y. Yamaguchi, S. Usui
    • Organizer
      Neuroinformatics 2015
    • Place of Presentation
      Cairns, Austlalia
    • Year and Date
      2015-08-20
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] A model based theory for the oculomotor velocity to position neural integration2015

    • Author(s)
      K. Inagaki, Y. Hirata
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      Kobe,JAPAN
    • Year and Date
      2015-07-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Different roles for ipsilateral positive feed back and commissural inhibitory networks in oculomotor velocity to position neural integration2015

    • Author(s)
      K. Inagaki, Y. Hirata
    • Organizer
      Annual Computational Neuroscience Meeting
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2015-07-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 眼球運動神経積分器を構成する両側性神経回路における同側フィードバックと対側抑制機構の役割評価2015

    • Author(s)
      稲垣圭一郎,平田豊
    • Organizer
      ニューロコンピューティング研究会
    • Place of Presentation
      沖縄科学技術大学院大学
    • Year and Date
      2015-06-23
    • Related Report
      2015 Research-status Report
  • [Presentation] 大規模数理モデル構築を目的とした共有モデル開発プラットフォーム:PLATO と 視覚情報処理解析への応用2015

    • Author(s)
      稲垣圭一郎,観音隆幸,神山斉己,石原彰人,臼井支朗
    • Organizer
      第54回生体医工学会大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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