| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
In this study, we examined the effects of food ingredients and epigenetic factors on pathological condition improvement in each condition of diet induced insulin resistance. It is suggested that β-carotene may lead to exacerbation of the disease state. It turned out that the effect of water - soluble dietary fiber pectin improvement depending on the content of pectin in the diet and the degree of glucose tolerance in type 2 diabetes rats. Inhibition of epigenetic factor BRD4 suppressed the effect of high fructose diet, however pathological condition could be exacerbated by excessive suppression of BRD4.
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