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Tuberculosis history from the relationship between cattle and human

Research Project

Project/Area Number 15K16272
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Sociology/History of science and technology
Research InstitutionNagasaki University

Principal Investigator

ICHIKAWA Tomoo  長崎大学, 熱帯医学研究所, 助教 (30508875)

Research Collaborator YAMAMOTO Taro  長崎大学, 熱帯医学研究所, 教授
WADA Takayuki  長崎大学, 熱帯医学研究所, 助教
MAEDA Shinji  北海道薬科大学, 薬学部, 教授
YANAI Tokuma  岐阜大学, 応用生物科学部, 教授
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords結核 / ウシ結核 / 医学史 / 分子疫学 / 人獣共通感染症 / M. bovis / M. tuberculosis / 畜牛結核 / ヒト結核 / 歴史統計
Outline of Final Research Achievements

This research organized data of historical statistics between 1905 and 1980 in order to analyze the impact of M.bovis to tuberculosis prevalence in Japan. As a result, this data reveals that bovine tuberculosis outbreak occurred in 1920 and 1940 especially around Kinki and Chugoku area. In addition, this research established detection system both of M.tuberculosis and M.bovis from FFPE sample. (①Extract DNA, ② to amplify and the DNA of IS6110 to detect TB, ③ to distinguish TB lineages by Realtime PCR ) The results of detection indicate that all FFPE specimen (299 samples)from TB patients were infected with M.tubelculosis, not M.bovis.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2016 2015

All Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] History of tuberculosis as zoonosis in Japan2016

    • Author(s)
      TOMOO ICHIKAWA
    • Organizer
      AAS-in-ASIA
    • Place of Presentation
      同志社大学(京都府京都市)
    • Year and Date
      2016-06-25
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ヒトとウシからみた日本の結核史:歴史統計によるprevalenceの把握2016

    • Author(s)
      市川智生
    • Organizer
      NIHUエコヘルス:近現代東アジアにおける「健康」の歴史研究ワークショップ
    • Place of Presentation
      首都大学東京(東京都・八王子市)
    • Year and Date
      2016-05-25
    • Related Report
      2016 Annual Research Report
  • [Presentation] Tuberculosis History from the Relationship between Cattle and Human: Mycobacterium Bovis and Modern Japan2015

    • Author(s)
      Tomoo Ichikawa
    • Organizer
      The Third Conference of East Asian Environmental History (EAEH 2015)
    • Place of Presentation
      Kagawa University (Kagawa)
    • Year and Date
      2015-10-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2018-03-22  

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