Effects of acute phase intensive exercise training in patients with acute decompensated heart failure. (ACTIVE-ADHF trial)
Project/Area Number |
15K16368
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | Kitasato University |
Principal Investigator |
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 早期運動療法 / 急性心不全 / 理学療法 |
Outline of Final Research Achievements |
Little is known about the effects of exercise based rehabilitation programs in acute heart failure (AHF) patients. We hypothesized that early rehabilitation would be efficacious in AHF patients. The ACTIVE-ADHF (Effects of acute phase intensive exercise training in patients with acute decompensated heart failure) trial is a multicenter, randomized con-trolled trial that will enroll patients from 3 hospitals in Japan. The primary endpoint of the trial is the change in 6-min walk distance between baseline and 2 weeks. Primary results of this trial are anticipated in 2019.
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Report
(4 results)
Research Products
(72 results)
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[Journal Article] Association between frailty and bone loss in patients undergoing maintenance hemodialysis2018
Author(s)
Kei Yoneki, Jun Kitagawa, Keika Hoshi, Manae Harada, Takaaki Watanabe, Takahiro Shimoda, Ryota Matsuzawa, Atsushi Yoshida, Yusuke Matsunaga, Yasuo Takeuchi, Kentaro Kamiya, Atsuhiko Matsunaga
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Journal Title
Journal of Bone and Mineral Metabolism
Volume: 2018 Jan 15
Issue: 1
Pages: 1-1
DOI
Related Report
Peer Reviewed
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[Journal Article] SARC‐F questionnaire identifies physical limitations and predicts post discharge outcomes in elderly patients with cardiovascular disease.2018
Author(s)
Shinya Tanaka, Kentaro Kamiya, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Yuta Ichinosawa, Manae Harada, Takeshi Nakamura, Emi Maekawa, Chiharu Noda, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Takashi Masuda, Junya Ako
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Journal Title
JCSM Clinical Reports
Volume: 3
Pages: 1-10
Related Report
Peer Reviewed / Open Access
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[Journal Article] Effects of acute phase intensive electrical muscle stimulation in frail elderly patients with acute heart failure (ACTIVE-EMS)2017
Author(s)
Shinya Tanaka, Kentaro Kamiya, Yuya Matsue, Yonezawa R, Saito H, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Wakaume K, Endo Y, Emi Maekawa, Minako Yamaoka-Tojo, Shiono T, Inomata T, Takashi Masuda, Junya Ako
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Journal Title
Clin Cardiol
Volume: 40
Issue: 12
Pages: 1189-1196
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Prognostic Value of Psoas Muscle Area and Density in Patients Who Undergo Cardiovascular Surgery2017
Author(s)
Masashi Yamashita, Kentaro Kamiya, Atsuhiko Matsunaga, Tadashi Kitamura, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Shinya Tanaka, Takeshi Nakamura, Emi Maekawa, Takashi Masuda, Junya Ako, Kagami Miyaji
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Journal Title
Canadian Journal of Cardiology
Volume: 33
Issue: 12
Pages: 1652-1659
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease.2017
Author(s)
Kamiya K, Hamazaki N, Matsue Y, Mezzani A, Corra U, Matsuzawa R, Nozaki K, Tanaka S, Maekawa E, Noda C, Yamaoka-Tojo M, Matsunaga A, Masuda T, Ako J.
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Journal Title
Eur J Prev Cardiol.
Volume: 印刷中
Issue: 2
Pages: 212-219
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Sarcopenia: prevalence and prognostic implications in elderly patients with cardiovascular disease2017
Author(s)
Kentaro Kamiya, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Shinya Tanaka, Yuta Ichinosawa, Emi Maekawa, Chiharu Noda, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Takashi Masuda, Junya Ako
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Journal Title
JCSM Clinical Reports
Volume: 2
Pages: 1-13
Related Report
Peer Reviewed / Open Access
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[Journal Article] Safety of neuromuscular electrical stimulation in patients implanted with cardioverter defibrillators.2016
Author(s)
Kamiya K, Satoh A, Niwano S, Tanaka S, Miida K, Hamazaki N, Maekawa E, Matsuzawa R, Nozaki K, Masuda T, Ako J.
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Journal Title
J Electrocardiol
Volume: 49
Issue: 1
Pages: 99-101
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Complementary Role of Arm Circumference to Body Mass Index in Risk Stratification in Heart Failure.2016
Author(s)
Kamiya K, Masuda T, Matsue Y, Inomata T, Hamazaki N, Matsuzawa R, Tanaka S, Nozaki K, Maekawa E, Noda C, Yamaoka-Tojo M, Matsunaga A, Izumi T, Ako J.
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Journal Title
JACC Heart Fail.
Volume: 4
Issue: 4
Pages: 265-273
DOI
Related Report
Peer Reviewed
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[Journal Article] Low-intensity resistance training with blood flow restriction improves vascular endothelial function and peripheral blood circulation in healthy elderly people.2016
Author(s)
Shimizu R, Hotta K, Yamamoto S, Matsumoto T, Kamiya K, Kato M, Hamazaki N, Kamekawa D, Akiyama A, Kamada Y, Tanaka S, Masuda T.
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Journal Title
Eur J Appl Physiol.
Volume: 116
Issue: 4
Pages: 749-757
DOI
Related Report
Peer Reviewed
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[Journal Article] Quadriceps Strength as a Predictor of Mortality in Coronary Artery Disease.2015
Author(s)
Kamiya K, Masuda T, Tanaka S, Hamazaki N, Matsue Y, Mezzani A, Matsuzawa R, Nozaki K, Maekawa E, Noda C, Yamaoka-Tojo M, Arai Y, Matsunaga A, Izumi T, Ako J.
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Journal Title
Am J Med
Volume: 128
Issue: 11
Pages: 1212-1219
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] 高齢循環器疾患患者におけるサルコペニア指標と心臓リハビリテーション2016
Author(s)
神谷健太郎, 増田卓, 濱崎伸明, 松沢良太, 田中伸弥, 野崎康平, 河野真理, 五十嵐亜希子, 岩村貴美, 前川恵美, 阿古潤哉
Organizer
日本循環器学会学術集会(日本サルコペニア・フレイル研究会-日本循環器学会ジョイントシンポジウム)
Place of Presentation
仙台
Year and Date
2016-03-18
Related Report
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[Presentation] Respiratory Muscle Weakness Elicits Inefficient Ventilation Resulting in the Deterioration of Exercise Intolerance in Patients with Chronic Heart Failure.2016
Author(s)
Nobuaki Hamazaki, Takashi Masuda, Kentaro Kamiya, Ryota Matsuzawa, Kohei Nozaki, Shinya Tanaka, Ayako Akiyama, Akihiro Aoyama, Kanae Yabu, Takeshi Nakamura, Emi Maekawa, Chiharu Noda, Minako Yamaoka-tojo, Junya Ako.
Organizer
The 80th Annual Scientific Meeting of the Japanese Circulation Society
Place of Presentation
Sendai
Year and Date
2016-03-18
Related Report
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[Presentation] Long-term Administration of Eicosapentaenoic Acid Prevents an Excessive Blood Pressure Elevation During Exercise Simulating Ordinary Activities of Daily Living via the Improvement of Vascular Endothelial Dysfunction in Patients With Hypertension.2015
Author(s)
A Aoyama, T Masuda, M Ogura, A Akiyama, Y Kamada, S Tanaka, K Kamiya, N Hamazaki, R Matsuzawa, K Nozaki, T Nakamura, K Yabu, E Maekawa, J Ako.
Organizer
American Heart Association Scientific Sessions
Place of Presentation
Orlando
Year and Date
2015-11-07
Related Report
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[Presentation] Increased Respiratory Muscle Strength Ameliorates Ventilation-perfusion Mismatch during Exercise via the Improvement of Inefficient Ventilation in Patients With Chronic Heart Failure.2015
Author(s)
N. Hamazaki, T. Masuda, K. Kamiya, R. Matsuzawa, K. Nozaki, S. Tanaka, A. Aoyama, K. Yabu, T. Nakamura, M. Tabata, E. Maekawa, C. Noda, M. Yamaoka-Tojo, J. Ako.
Organizer
American Heart Association Scientific Sessions
Place of Presentation
Orlando
Year and Date
2015-11-07
Related Report
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[Presentation] 下腿の周径は心不全患者の生命予後を予測する.2015
Author(s)
神谷健太郎, 増田卓, 濱崎伸明, 松沢良太, 田中伸弥, 野崎康平, 岩村貴美, 河野真理, 五十嵐亜希子, 前川恵美, 野田千春, 東條美奈子, 猪又孝元, 松永篤彦, 阿古潤哉.
Organizer
第21回日本心臓リハビリテーション学会
Place of Presentation
福岡
Year and Date
2015-07-18
Related Report
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[Presentation] 入院期にフレイルを合併した高齢心不全患者では退院後の運動耐容能の回復が著しく阻害される.2015
Author(s)
野崎康平, 増田卓, 神谷健太郎, 濱崎伸明, 松沢良太, 田中伸弥, 岩村貴実, 河野真理, 五十嵐亜希子, 前川恵美, 野田千春, 東條美奈子, 阿古潤哉.
Organizer
第21回日本心臓リハビリテーション学会学術集会
Place of Presentation
福岡
Year and Date
2015-07-18
Related Report
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[Presentation] 心不全患者の入院早期に評価した10m快適歩行時の最高心拍数は, 心不全再入院と心臓死の予測因子となる.2015
Author(s)
前川恵美, 増田卓, 田中伸弥, 野崎康平, 松沢良太, 濱嵜伸明, 神谷健太郎, 五十嵐亜希子, 河野真理, 岩村貴美, 野田千春, 猪又孝元, 東條美奈子, 阿古潤哉.
Organizer
第21回日本心臓リハビリテーション学会学術集会.
Place of Presentation
福岡
Year and Date
2015-07-18
Related Report
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[Presentation] 下肢筋力は心血管疾患患者の長期予後を予測する.2015
Author(s)
神谷健太郎, 増田卓, 田中伸弥, 濱崎伸明, 松沢良太, 野崎康平, 河野真理, 五十嵐亜希子, 岩村貴美, 前川恵美, 野田千春, 末永祐哉, 松永篤彦, 東條美奈子, 和泉徹, 阿古潤哉.
Organizer
第51回日本循環器病予防学会学術集会
Place of Presentation
大阪
Year and Date
2015-06-26
Related Report
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[Presentation] Chronic Kidney Disease Stage 3 or 4 Disturbs the Accomplishment of Optimum Physical Activity in Patients with Ischemic Heart Disease.2015
Author(s)
Matsuzawa R, Masuda T, Kamiya K, Hamazaki N, Nozaki K, Tanaka S, Kawano M, Aoyama A, Noda C, Yamaoka-Tojo M, Maekawa E, Ako J
Organizer
The 79th Annual Scientific Meeting of the Japanese Circulation Society
Place of Presentation
Osaka
Year and Date
2015-04-24
Related Report
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