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Exploring cortical inhibitory process following weak peripheral nerve stimuli and its clinical application : an MEG study

Research Project

Project/Area Number 15K16385
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionHiroshima University

Principal Investigator

Nakagawa Kei  広島大学, 医歯薬保健学研究科(保), 助教 (10711070)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords脳磁図 / 感覚刺激 / 抑制系 / リハビリテーション / 半球間抑制
Outline of Final Research Achievements

In the present study, we aimed to explore the neurophysiological mechanism of the cortical inhibitory process and to establish a new method for evaluation using weak peripheral nerve repetitive electrical stimuli. As a result, we were able to demonstrate a possibility to evaluate intra- and inter- cortical inhibition of the somatosensory area by using a magnetoencephalography with excellent temporal and spatial resolution. These results will be helpful in further evaluation for the central nervous system diseases. In addition, we found the possibility that voluntary movement could modulate the inter-hemispheric inhibition of the somatosensory area.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (5 results) (of which Invited: 3 results) Book (1 results)

  • [Journal Article] 特集 再生医療とリハビリテーション 再生医療とリハビリテーションの動向2017

    • Author(s)
      弓削 類, 猪村剛史, 中川 慧
    • Journal Title

      総合リハビリテーション

      Volume: 45 Issue: 1 Pages: 5-11

    • DOI

      10.11477/mf.1552200813

    • ISSN
      0386-9822, 1882-1340
    • Year and Date
      2017-01-10
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 脳機能マッピングからの感覚・運動機能の評価 ―脳磁図を用いた報告―2017

    • Author(s)
      中川 慧,猪村剛史,弓削 類
    • Journal Title

      日本基礎理学療法学雑誌

      Volume: 20 Pages: 31-36

    • NAID

      130007490600

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Neuromagnetic evaluation of communication support system for hearing-impaired subjects.2017

    • Author(s)
      Nakagawa K., Nakaishi S., Imura T., Kawahara Y., Hashizume A., Kurisu K., Yuge L.
    • Journal Title

      Neuroreport

      Volume: 28 Issue: 12 Pages: 712-719

    • DOI

      10.1097/wnr.0000000000000817

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 末梢神経連発刺激による脳内抑制過程の探索2018

    • Author(s)
      中川 慧,弓削 類
    • Organizer
      第33回日本生体磁気学会大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 感覚・運動関連脳磁界を指標としたリハビリテーション介入効果の検証2017

    • Author(s)
      中川 慧
    • Organizer
      第47回日本臨床神経生理学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 脳機能マッピングからの感覚・運動機能の評価 ―脳磁図を用いた報告―2016

    • Author(s)
      中川 慧
    • Organizer
      第51回日本理学療法学術大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-05-27
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 末梢神経刺激が大脳皮質抑制系へ及ぼす影響―異なる神経へ先行刺激を与えた際の脳磁場応答の検討―2015

    • Author(s)
      中川 慧
    • Organizer
      第17回日本ヒト脳機能マッピング学会
    • Place of Presentation
      毎日新聞オーバルホール(大阪府大阪市)
    • Year and Date
      2015-07-02
    • Related Report
      2015 Research-status Report
  • [Presentation] 微弱な末梢神経刺激が大脳皮質抑制機構へ及ぼす影響―異なる末梢神経先行刺激を与えた際の脳磁場応答の検討―2015

    • Author(s)
      中川 慧
    • Organizer
      第50回日本理学療法学学術大会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2015-06-05
    • Related Report
      2015 Research-status Report
  • [Book] 再生医療とリハビリテーション2018

    • Author(s)
      川平和美,弓削 類,紀ノ岡正博,福角勇人,中川誠人,光原崇文,本望修,高橋信也,土井大輔,松山オジョス武,阪上守人,澤芳樹,中田研,山海嘉之,田中英一郎,下堂薗恵,勝俣良紀,中川慧
    • Total Pages
      190
    • Publisher
      三輪書店
    • ISBN
      9784895906289
    • Related Report
      2017 Annual Research Report

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Published: 2015-04-16   Modified: 2019-03-29  

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