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Neural substrates and cognition associated with daily physical activity in older persons with cognitive decline

Research Project

Project/Area Number 15K16387
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionChukyo University (2016-2017)
National Center for Geriatrics and Gerontology (2015)

Principal Investigator

HARADA Kenji  中京大学, 体育学研究科, 実験実習助手 (70736058)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords高齢者 / 身体活動 / 脳構造 / 脳活動 / resting state / VBM / DTI / 身体活動量 / fMRI / 安静時脳機能結合 / 認知機能低下 / 認知機能 / TBSS / MRI / 拡散テンソル画像
Outline of Final Research Achievements

The present study aimed to elucidate relationships between daily physical activity and neural substrates in an elderly, cognitively declining population. Those with high levels of physical activity had greater functional connectivity during a resting brain state than those with lower levels of physical activity. In addition, there were no significant differences or correlations between daily physical activity and gray matter density or white matter integrity. However, elders with higher levels of physical activity had a trend of smaller left parahippocampal volumes, as compared to those with low levels of physical activity.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2016 2015

All Presentation (3 results)

  • [Presentation] 認知機能が低下した高齢者における日常の身体活動量の違いによる脳容積の違い2016

    • Author(s)
      原田健次、裴成琉、朴眩泰、李相侖、李成喆、原田和弘、牧迫飛雄馬、島田裕之
    • Organizer
      第58回日本老年医学会学術集会
    • Place of Presentation
      石川県立音楽堂
    • Year and Date
      2016-06-08
    • Related Report
      2016 Research-status Report
  • [Presentation] 認知機能が低下した高齢者における日常の身体活動量の違いによる脳容積の違い2016

    • Author(s)
      原田健次、裵成琉、朴眩泰、李相侖、李成喆、原田和弘、牧迫飛雄馬、島田裕之
    • Organizer
      日本老年医学会
    • Place of Presentation
      石川県立音楽堂ほか
    • Year and Date
      2016-06-08
    • Related Report
      2015 Research-status Report
  • [Presentation] 認知機能が低下した高齢者における日常の身体活動強度の違いによる白質構造の違い2015

    • Author(s)
      原田健次、裵 成琉、李 相侖、李 成喆、原田和弘、島田裕之、鈴木隆雄
    • Organizer
      日本老年医学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-06-12
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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