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Relationship between functional maturation of spinal motor neuron and spontaneous movements in early infancy

Research Project

Project/Area Number 15K16417
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Developmental mechanisms and the body works
Research InstitutionThe University of Tokyo

Principal Investigator

Kanazawa Hoshinori  東京大学, 大学院情報理工学系研究科, 特別研究員 (60744993)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords運動発達 / 新生児 / 乳児 / 自発運動 / 筋電図 / 脊髄運動神経 / 運動単位 / 脳波 / 神経成熟
Outline of Final Research Achievements

Although human infantile movement patterns have been well characterized, little is known about the characteristics of motor output and sensory feedback during their movements. Firstly, we developed multi-channel surface electromyogram electrode made from silicon material for delicate skin of human neonate/infant. Secondly, we combined the measured kinematics and infantile musculoskeletal model, and found that calculated pair-wise correlations of muscle lengths between each two muscles were higher in infant than neonate, especially in upper and lower limbs muscle.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (12 results)

All 2018 2017 2016 Other

All Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (5 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results) Remarks (2 results)

  • [Journal Article] Modulation of EMG-EMG Coherence in a Choice Stepping Task2018

    • Author(s)
      Nojima Ippei、Watanabe Tatsunori、Saito Kotaro、Tanabe Shigeo、Kanazawa Hoshinori
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 12 Pages: 111-111

    • DOI

      10.3389/fnhum.2018.00050

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Validity of spectral analysis based on heart rate variability from 1-minute or less ECG recordings2017

    • Author(s)
      Takahashi Naomi、Kuriyama Akira、Kanazawa Hoshinori、Takahashi Yoshimitsu、Nakayama Takeo
    • Journal Title

      Pacing and clinical electrophysiology

      Volume: 40 Issue: 9 Pages: 1004-1009

    • DOI

      10.1111/pace.13138

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 構成論的発達科学2017

    • Author(s)
      國吉 康夫,長井 志江,小西 行郎,明和 政子,熊谷 晋一郎,大村 吉幸,金沢 星慶
    • Journal Title

      ベビーサイエンス

      Volume: 17

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 運動機能発達の脳・神経科学的メカニズム解明の成果と小児理学療法への応用の手がかり2017

    • Author(s)
      儀間 裕貴,金沢 星慶
    • Journal Title

      理学療法学

      Volume: 34

    • Related Report
      2017 Annual Research Report
  • [Journal Article] An Embodied Brain Model of the Human Foetus.2016

    • Author(s)
      Yamada Y, Kanazawa H, Iwasaki S, Tsukahara Y, Iwata O, Yamada S, Kuniyoshi Y.
    • Journal Title

      Scientific Reports

      Volume: 15;6 Issue: 1 Pages: 27893-27893

    • DOI

      10.1038/srep27893

    • NAID

      120006349332

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Single Laser to Multiple Optical Fiber Device for Optogenetics-based Epidural Spinal Cord Stimulation2017

    • Author(s)
      Shih-Yin Chang*, Kazunori Naganuma, Hoshinori Kanazawa, Kenta Takashima, Kuniaki Konishi, Takao Someya, Masaki Sekino, Yasuo Kuniyoshi, Hiroshi Onodera
    • Organizer
      8th International IEEE EMBS Neural Engineering Conference
    • Place of Presentation
      Regal International East Asia Hotel, Shanghai, China
    • Year and Date
      2017-05-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Single Laser to Multiple Optical Fiber Device for Optogenetics-based Epidural Spinal Cord Stimulation2017

    • Author(s)
      Shih-Yin Chang, Kazunori Naganuma, Hoshinori Kanazawa, Kenta Takashima, Kuniaki Konishi, Takao Someya, Masaki Sekino, Yasuo Kuniyoshi, Hiroshi Onodera
    • Organizer
      The 8th International IEEE EMBS Conference on Neural Engineering
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Predictive Codingを用いた運動主体感の獲得モデル2017

    • Author(s)
      森岡 智陽、金沢 星慶、米倉 将吾、藤井 敬子、國吉 康夫
    • Organizer
      第17回日本赤ちゃん学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 自発運動の発達的変化に潜む全身運動感覚と神経学的構造の関連性2016

    • Author(s)
      金沢 星慶,山田 康智,田中 一敏,河井 昌彦,國吉 康夫
    • Organizer
      発達神経科学学会
    • Place of Presentation
      東京都文京区本郷,東京大学本郷キャンパス,武田先端知ビル
    • Year and Date
      2016-11-26
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Information structure of proprioceptive feedback in infantile spontaneous movements2016

    • Author(s)
      H Kanazawa, Y Yamada, K Kuniyoshi
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego,Convention Center, USA
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Remarks] ISI's HP

    • URL

      http://www.isi.imi.i.u-tokyo.ac.jp/index.html

    • Related Report
      2016 Research-status Report
  • [Remarks] Kanazawa's HP

    • URL

      http://www.isi.imi.i.u-tokyo.ac.jp/~kanazawa/

    • Related Report
      2016 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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