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The role of bone marrow cells in obtaining the effect of exercise

Research Project

Project/Area Number 15K16491
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionTokyo University of Agriculture

Principal Investigator

TADAISHI MIKI  東京農業大学, 応用生物科学部, 助教 (50633799)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords骨髄 / 運動 / 運動トレーニング
Outline of Final Research Achievements

Exercise is known to influence whole body, contributing to health maintenance, disease prevention, improvement of quality of life. A variety of cell types are present in the bone marrow, and in recent years the possibility of working as an endocrine organ has also been shown, but the relationship with the exercise is not clear. Therefore, this study aimed to investigate the relationship between exercise and bone marrow. As a result, we established a method for preparing frozen tissue sections useful for analysis of bone marrow - bone - skeletal muscle crosstalk. In addition, expression change of mRNA level was observed after exercise in both skeletal muscle and bone marrow, indicating that exercise has an effect on bone marrow.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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