| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
The purpose of this study is to elucidate the anti oxidant efffect mechanism of hydrogen through confirming the effect of molecular hydrogen on epigenetic abnormality in lifestyle - related diseases.
Cells were used to ascertain the effect of molecular hydrogen under conditions causing epigenetic abnormality. As a result, it was confirmed that molecular hydrogen changes epigenetics including activation of HDAC. However, it was not possible to examine the effect of moluecular hydrogen by using a high-fat diet intake animal model, and the existence of epigenetic change in an animal model has time to establish a methodology, and at the stage of comparing and examining It did not arrive.
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