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Can skeletal muscle echo intensity reflecting muscle composition be used as a new sarcopenia index

Research Project

Project/Area Number 15K16531
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionDoshisha University (2016-2017)
Kyoto Gakuen University (2015)

Principal Investigator

Watanabe Yuya  同志社大学, スポーツ健康科学部, 助教 (70644376)

Research Collaborator KIMURA Misaka  京都学園大学, 健康医療学部, 教授 (90150573)
YOSHINAKA Yasuko  京都学園大学, 経済経営学部, 教授 (80166983)
YAMADA Yosuke  国立研究開発法人医薬基盤・健康・栄養研究所, 研究員 (60550118)
IKENAGA Masahiro  福岡大学, スポーツ科学部, 助教 (90735573)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsエコー輝度 / フレイル / 超音波 / 筋輝度 / 筋内組成 / サルコペニア
Outline of Final Research Achievements

Echo intensity (EI) calculated from skeletal muscle ultrasonography (US) images has been considered to reflect muscle quality. The purpose of this study was to explore the applicability of EI as a sarcopenia / frail index. In the main research, 1,319 older adults (649 men, 670 women) were divided into robust, pre-frail and frail groups, and thus, their front-thigh US data [muscle thickness (MT) and EI] were compared. Significant linear trends were observed in MT and EI for both sex.
The findings suggest the utility of EI as a muscle composition index. Because EI can detect the quantitative and qualitative changes in skeletal muscle even at the pre-frail stage, it is expected to be use as a screening tool in the field of preventing frail and long-term care.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (8 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Comprehensive geriatric intervention program with and without weekly class-style exercise: Research protocol of a cluster randomized control trial in Kyoto-Kameoka Study2018

    • Author(s)
      Watanabe Y, Yamada Y, Yokoyama K, Yoshida T, Yoshinaka Y etc
    • Journal Title

      Clinical Interventions in Aging

      Volume: 13 Pages: 1019-1033

    • DOI

      10.2147/cia.s151427

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 質問紙によるフレイル判定と超音波法を用いた下肢骨格筋の量的・質的指標の関連2017

    • Author(s)
      渡邊裕也, 吉田司, 山田陽介, 横山慶一, 山縣恵美, 三宅基子, 吉中康子, 岡山寧子, 木村みさか
    • Organizer
      第4回日本サルコペニア・フレイル学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The cost-effectiveness of an exercise-based comprehensive intervention in older adults2017

    • Author(s)
      Yuya Watanabe, Tsukasa Yoshida, Miwa Yamaguchi, Yosuke Yamada, Misaka Kimura
    • Organizer
      10th International Conference on Cachexia, Sarcopenia & Muscle Wasting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 地域在住高齢者が安全で手軽に実践できるレジスタンスエクササイズ2016

    • Author(s)
      渡邊裕也
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      盛岡地域交流センター(盛岡)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 筋発揮張力維持スロー法を応用した自体重運動の乳酸応答2016

    • Author(s)
      渡邊裕也
    • Organizer
      第26回体力・栄養・免疫学会大会
    • Place of Presentation
      長崎大学 (長崎)
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
  • [Presentation] Relationship between gait function and skeletal muscle quantity or quality assessed by ultrasonography and echo intensity in healthy older men.2016

    • Author(s)
      Yamada Y, Watanabe Y, Fukumoto Y, Yokoyama K, Yoshida T, Yamagata E, Yamada M, Kimura M
    • Organizer
      The International Conference on Frailty & Sarcopenia Research 2016
    • Place of Presentation
      Philadelphia(USA)
    • Year and Date
      2016-04-28
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 超音波法を用いた量的・質的骨格筋評価-自立度や活動性が異なる高齢者の比較―2016

    • Author(s)
      渡邊裕也, 田宮創, 續田尚美, 田村由馬, 安隆則, 山縣恵美, 山田陽介, 吉中康子, 木村みさか
    • Organizer
      第3回日本サルコペニア・フレイル研究会研究発表会
    • Place of Presentation
      今池ガスビル(名古屋)
    • Related Report
      2016 Research-status Report
  • [Presentation] リズム体操を含む多要素複合プログラムが高齢者の体力に及ぼす効果2015

    • Author(s)
      渡邊裕也、横山慶一、吉中康子、木村みさか
    • Organizer
      日本体操学会第15回学会大会
    • Place of Presentation
      京都学園大学
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
  • [Presentation] 日常生活の歩数が地域在住高齢者の骨格筋量および質に及ぼす影響2015

    • Author(s)
      渡邊裕也、山田陽介、横山慶一、吉田司、三宅基子、山縣恵美、岡山寧子、吉中康子、木村みさか
    • Organizer
      第57回日本老年医学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-06-12
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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