| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
In this study, we used the visual imprinting behavior of chicks as a learning model and aimed at elucidating the mechanism of high neural plasticity in juvenile learning. With comprehensive gene expression analysis, we identified some peptides included a diuretic peptide family were highly expressed in the brain region, which was important for imprinting learning, at the time when imprinting can be established (critical period). And the expression level of these genes were changed after imprinting learning. Moreover, Improvement in efficiency of imprinting learning and prolongation of the critical period were observed by injection of the peptide into the brain. Analysis of the binding ability of the peptides of chicks was performed.
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