| Project/Area Number |
15K17334
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Experimental psychology
|
|---|
| Research Institution | Tokyo Metropolitan Institute of Medical Science |
|---|
Principal Investigator |
HIROAKI Ishida 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 主任研究員 (70728162)
|
|---|
| Research Collaborator |
GRANDI Laura Clara University of Parma, Department of Neuroscience, Unit of Physiology, 大学院生
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | 感覚運動統合 / 島皮質 / 運動前野 / 頭頂葉 / 扁桃体 / 大脳基底核 / 狂犬病ウイルス / 単一ニューロン活動 / 身体意識 / 腹側運動前野 / 社会的認知 / 大脳辺縁系 / マカクザル / 下頭頂小葉 / 統合失調症 / ミラーメカニズム |
|---|
| Outline of Final Research Achievements |
The aims of the present project were to investigate; 1) the neural activity within the premotor-insula-parietal regions in the macaque monkey; 2) the neural network between the ventral premotor (PMv) areas and the basal ganglia (BG) or the amygdala (Amyg). To this purpose monkeys were tested in sensory (visual, somatosensory)-motor tasks. Further, we employed retrograde transneuronal labeling with rabies virus to identify the origins of multisynaptic projections from the BG/Amyg to the PMv in macaque monkeys. As so for, the results showed that neurons in the insular cortex were active during hand-mouth movement and during passive tactile stimulation. Further, PMv receives inputs from motor and limbic territories of BG/Amyg. Our results suggested that the frontal-parietal network is involved in both motor and limbic cognitions.
|
