Fused oligomers of a macrocycle with dynamic figure eight chirality
Project/Area Number |
15K17818
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Organic chemistry
|
Research Institution | Hokkaido University |
Principal Investigator |
Katoono Ryo 北海道大学, 理学研究院, 助教 (60432142)
|
Research Collaborator |
TANAKA Yuki
KAWAI Shunsuke
KUSAKA Keiichi
OBARA Yudai
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 動的キラリティ / マクロサイクル / テレフタルアミド / 縮環多量体 / 縮環オリゴマー / 動的8の字キラリティ / 縮環型オリゴマー |
Outline of Final Research Achievements |
I have newly designed a series of fused oligomers of macrocycles with dynamic figure eight chirality. Dynamic features in solution of these fused oligomers were investigated through NMR, UV and CD spectroscopy. For fused oligomers, the barrier to dynamic interconversion between two helical conformations with M- or P-helicity followed a specific pattern similar to that of the original unit of a macrocycle. Complexation and chiroptical properties were dependent on the molecular shape, that is a manner of fusion. We found a new perspective on "chiral amplification". In a fused trimer or a tetramer, the helical-sense preference increased with the number of units. These finding was brought about by quantitative observation of the helical-sense preferences through NMR spectroscopy in solution.
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Report
(4 results)
Research Products
(19 results)