Direct C-N Bond Formation Using I-N Bonding Hypervalent Iodine
Project/Area Number |
15K17819
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Organic chemistry
|
Research Institution | Chiba University |
Principal Investigator |
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | アミノ化反応 / 複素環化合物 / 超原子価ヨウ素 / ハロゲン化 / ヨウ素 / アミノ化 / インドール / 超原子価化合物 |
Outline of Final Research Achievements |
We have developed the design of I-N bonding hypervalent iodine compounds and the direct amination of heterocycles using these compounds as low environmental load type transformation in this work. As a result, Csp2-Csp2 bromoamination, remote Csp2-Csp3 iodoamination, and catalytic 3-amination of indole derivatives were accomplished by handling I-N bonding hypervalent iodine compounds. Furthermore, synthesis of various amino-substituted indole derivatives from products of these transformations were succeeded.
|
Report
(4 results)
Research Products
(39 results)