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Elastic modulus and micro- and nano-structure of a single trabecula

Research Project

Project/Area Number 15K17929
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Materials/Mechanics of materials
Research InstitutionHokkaido University

Principal Investigator

Yamada Satoshi  北海道大学, 工学研究院, 助教 (90730169)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsバイオメカニクス / 骨組織 / 強度 / 海綿骨 / 骨梁 / ハイドロキシアパタイト
Outline of Final Research Achievements

The study aims to propose a novel experimental method for the mechanical properties of a single trabecula by micro-cantilever bending and to investigate the elastic modulus and the micro- and nano-structure of a single trabecula in the bovine cancellous bone. As a result, elastic modulus of the single trabeculae was significantly smaller than that of the cortical bone specimens. The c-axis of the hydroxyapatite crystals in a single trabecula aligned along the longitudinal direction of the trabecula, not the bone axis. The elastic modulus did not correlate with the degree of crystal orientation, although there was a statistically significant correlation in the bone tissue including the single trabeculae and the cortical bone specimens.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (10 results)

All 2017 2016 2015 Other

All Journal Article (2 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 2 results) Presentation (6 results) (of which Int'l Joint Research: 3 results) Remarks (2 results)

  • [Journal Article] Micro-cantilever bending for elastic modulus measurements of a single trabecula in cancellous bone2016

    • Author(s)
      Satoshi Yamada, Shigeru Tadano, Koichi Fukasawa
    • Journal Title

      Journal of Biomechanics

      Volume: 49 Issue: 16 Pages: 4124-4127

    • DOI

      10.1016/j.jbiomech.2016.10.016

    • NAID

      120006367984

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Micro Cantilever Bending for Elastic Modulus of Single Trabecula2015

    • Author(s)
      Satoshi Yamada, Koichi Fukasawa, Masahiro Todoh, Shigeru Tadano
    • Journal Title

      Proceedings of the 8th Asian-Pacific Conference on Biomechanics

      Volume: - Pages: 306-306

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Presentation] Elastic modulus and hydroxyapatite crystal orientation in a single trabecula2017

    • Author(s)
      Satoshi Yamada, Koichi Fukasawa, Masahiro Todoh, Shigeru Tadano
    • Organizer
      The XXVI Congress of the International Society of Biomechanics (ISB2017)
    • Place of Presentation
      Brisbane Convention & Exhibition Centre, Brisbane, Australia
    • Year and Date
      2017-07-23
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ウシ大腿骨単一骨梁における弾性率と HAp 結晶配向性の関係と皮質骨との比較2017

    • Author(s)
      山田悟史, 深沢光一, 東藤正浩, 但野茂
    • Organizer
      日本機械学会第29回バイオエンジニアリング講演会
    • Place of Presentation
      ウインクあいち, 愛知県名古屋市
    • Year and Date
      2017-01-19
    • Related Report
      2016 Annual Research Report
  • [Presentation] Elastic modulus of single trabecula in bovine cancellous bone by micro cantilever bending2016

    • Author(s)
      Satoshi Yamada, Koichi Fukasawa, Shigeru Tadano
    • Organizer
      22nd Congress of the European Society of Biomechanics (ESB2016)
    • Place of Presentation
      Lyon Convention Centre, Lyon, France
    • Year and Date
      2016-07-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ウシ大腿骨皮質骨オステオンレベルの弾性率分布2016

    • Author(s)
      山田悟史、東藤正浩、但野茂
    • Organizer
      日本機械学会第28回バイオエンジニアリング講演会
    • Place of Presentation
      東京工業大学、東京都目黒区
    • Year and Date
      2016-01-09
    • Related Report
      2015 Research-status Report
  • [Presentation] Micro Cantilever Bending for Elastic Modulus of Single Trabecula2015

    • Author(s)
      Satoshi Yamada, Koichi Fukasawa, Masahiro Todoh, Shigeru Tadano
    • Organizer
      The 8th Asian-Pacific Conference on Biomechanics (AP Biomech 2015)
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Micro Cantilever Bendingによる海綿骨骨梁単体の弾性率計測2015

    • Author(s)
      深沢光一、山田悟史、東藤正浩、但野茂
    • Organizer
      日本機械学会2015年度年次大会
    • Place of Presentation
      北海道大学、北海道札幌市
    • Year and Date
      2015-09-15
    • Related Report
      2015 Research-status Report
  • [Remarks] 北海道大学工学系連携推進部研究者紹介

    • URL

      http://labs.eng.hokudai.ac.jp/office/elo/jp/archives/labo/4916/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 北海道大学工学系連携推進部研究者紹介:骨組織の力学的特性と階層構造特性の関係

    • URL

      http://labs.eng.hokudai.ac.jp/office/elo/jp/archives/labo/4916/

    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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