| Project/Area Number |
15K18245
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Material processing/Microstructural control engineering
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| Research Institution | Okayama University |
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Principal Investigator |
Shinonaga Togo 岡山大学, 自然科学研究科, 助教 (60748507)
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| Research Collaborator |
TSUKAMOTO Masahiro 大阪大学, 接合科学研究所, 教授 (90273713)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | フェムト秒レーザ / 周期的微細構造 / 生体材料 / チタン / 骨芽細胞 / 細胞伸展制御 / 細胞伸展 |
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| Outline of Final Research Achievements |
Titanium alloys are the most used biomaterials. However, they have insufficient bioactivity. Therefore, it is required to add new function to titanium alloys. One method to add new function is the creation of periodic nanostructures on the surfaces, which can control cell spreading. Then, femtosecond laser is one of the useful tools to create periodic nanostructures which can be created on various metals by self-organizing in the laser focusing spot.
In this study, control of cell spreading on titanium material was examined by periodic nanostructures formation with femtosecond laser. It is clarified that period of the periodic nanostructures can be varied by laser wavelength. Then, cell test was conducted by using the titanium material which have periodic nanostructures with different periods. Results of cell test show that periods of about 300 and 600 nm are useful for control of cell spreading on titanium material surface.
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