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Functinal role of fine-scale networks in the primary visual cortex

Research Project

Project/Area Number 15K18351
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Neurophysiology / General neuroscience
Research InstitutionNational Institute for Physiological Sciences

Principal Investigator

ISHIKAWA Ayako  生理学研究所, 基盤神経科学研究領域, 助教 (60547991)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords神経回路 / 一次視覚野 / 発達 / 同期発火 / 可塑性 / 視覚野 / 神経活動同期生 / 生後発達 / 同期活動 / 視覚反応性 / ラット
Outline of Final Research Achievements

Fine-scale networks composed of a population of interconnected neurons are embedded in a small area in rat visual cortex. To clarify the function of the network, we used rats with different developmental conditions and investigated neural activity patterns in the presence and absence of the networks in the primary visual cortex. Neuron pairs with similar visual feater selectivities fired in synchrony only when the networks were presence. These data suggest that the fine-scale networks might contribute to the feature selective synchronous firing in the primary visual cortex.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (10 results)

All 2017 2016 2015

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (8 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Activation of SF1 Neurons in the Ventromedial Hypothalamus by DREADD Technology Increases Insulin Sensitivity in Peripheral Tissues.2017

    • Author(s)
      Coutinho EA, Okamoto S, Ishikawa AW, Yokota S, Wada N, Hirabayashi T, Saito K, Sato T, Takagi K, Wang CC, Kobayashi K, Ogawa Y, Shioda S, Yoshimura Y, Minokoshi Y
    • Journal Title

      Diabetes

      Volume: 66 Issue: 9 Pages: 2372-2372

    • DOI

      10.2337/db16-1344

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Microglia contact induces synapse formation in developing somatosensory cortex.2016

    • Author(s)
      Miyamoto A, Wake H, Ishikawa AW, Eto K, Shibata K, Murakoshi H, Koizumi S, Moorhouse AJ, Yoshimura Y, Nabekura J
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 1-12

    • DOI

      10.1038/ncomms12540

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Visual experience is required for establishing feature-selective synchronization in the upper but not lower layer in primary visual cortex2017

    • Author(s)
      Ayako Ishikawa,Yumiko Yoshimura
    • Organizer
      第48回 生理研国際シンポジウム Neural circuitry and plasticity underlying brain function
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大脳皮質領野間結合の経験依存的な発達2016

    • Author(s)
      石川理子,吉村由美子
    • Organizer
      第63回 中部日本生理学会
    • Place of Presentation
      愛知、岡崎、生理学研究所
    • Year and Date
      2016-11-04
    • Related Report
      2016 Research-status Report
  • [Presentation] Visual experience-dependent and independent development of visually-evoked synchronized firing in rat visual cortex2016

    • Author(s)
      Ayako W Ishikawa,Yukio Komatsu,Yumiko Yoshimura
    • Organizer
      第39回 日本神経科学大会
    • Place of Presentation
      神奈川、横浜、パシフィコ横浜
    • Year and Date
      2016-07-20
    • Related Report
      2016 Research-status Report
  • [Presentation] ラット視覚野における視覚経験依存的・非依存的な同期発火の生後発達2016

    • Author(s)
      石川理子
    • Organizer
      第39回日本神経科学会
    • Place of Presentation
      パシフィコ横浜.
    • Year and Date
      2016-07-20
    • Related Report
      2015 Research-status Report
  • [Presentation] 大脳皮質一次視覚野における神経細胞の同期発火形成の解析2015

    • Author(s)
      石川理子
    • Organizer
      第62回中部日本生理学会
    • Place of Presentation
      富山大学
    • Year and Date
      2015-11-15
    • Related Report
      2015 Research-status Report
  • [Presentation] Visual experience-dependent development of fine-scale networks and synchronous firing in the rat primary visual cortex2015

    • Author(s)
      Ayako Ishikawa
    • Organizer
      the NIPS-CIN Joint Symposium
    • Place of Presentation
      岡崎カンファレンスセンター
    • Year and Date
      2015-11-14
    • Related Report
      2015 Research-status Report
  • [Presentation] Experience-dependent and independent development of feature-selective synchronization in rat visual cortex2015

    • Author(s)
      Ayako Ishikawa
    • Organizer
      Neuroscience 2015
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2015-10-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Experience-dependent development of fine-scale networks and synchronous firing in the rat primary visual cortex2015

    • Author(s)
      Ayako Ishikawa
    • Organizer
      第38回日本神経科学学会サテライトシンポジウム
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-07-27
    • Related Report
      2015 Research-status Report
    • Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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