The search for the plant-specific autophagy deficient strain using arabidopsis thaliana T-DNA insertion lines.

• Project/Area Number: 15K18526
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Cell biology
• Research Institution: Saitama University
• Principal Investigator: INOUE Yuko 埼玉大学, 理工学研究科, 助教 (40637922)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: オートファジー / シロイヌナズナ

Outline of Final Research Achievements

Macroautophagy (hereafter autophagy) is well conserved mechanism for eukaryotes which degraded the part of their cell component under nutrient deficient conditions. In plants, autophagy is induced not only under nutrient-starvation conditions but also various stresses. It is understood that autophagy is induced in the Arabidopsis root elongation region even in the presence of nutritions, but the mechanism of the induction is unclear.
Therefore, in this study, I carried out the screening of plant-specific autophagy-related gene mutants. Although I could not find the novel autophagy-related genes within the term of research fund, I continue the primary screening.