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The analysis of new mitosis regulating protein LUZP1

Research Project

Project/Area Number 15K18528
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Cell biology
Research InstitutionNagoya University

Principal Investigator

HYODO Toshinori  名古屋大学, 医学系研究科, 研究員 (40710645)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords細胞分裂
Outline of Final Research Achievements

All cells need to divide for an increase in its number. Cancer or bacteria that get worse by increasing in cell numbers also do it. If we can control it, we will suppress these diseases. But the mechanisms of cell division still remain largely unknown.
We tried to find new cell division regulating proteins and finally we focused LUZP1 that function is unknown. In this research, we revealed that LUZP1 regulates cytokinesis that is the last step of cell division and may bridge the important two signal pathways during cell division.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2016

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results)

  • [Journal Article] A regulatory subunit of protein phosphatase 2A, PPP2R5E, regulates the abundance of microtubule crosslinking factor 1.2016

    • Author(s)
      Hyodo T, Ito S, Asano-Inami E, Chen D, Senga T.
    • Journal Title

      FEBS J

      Volume: 283 Issue: 19 Pages: 3662-3671

    • DOI

      10.1111/febs.13835

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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