Project/Area Number |
15K18564
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Plant molecular biology/Plant physiology
|
Research Institution | Institute of Physical and Chemical Research |
Principal Investigator |
Ikeuchi Momoko 国立研究開発法人理化学研究所, 環境資源科学研究センター, 基礎科学特別研究員 (00633570)
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
|
Keywords | 細胞分裂 / 細胞分化 / 再生 / 細胞リプログラミング / 細胞分化の維持機構 / エピジェネティクス |
Outline of Final Research Achievements |
Plant cells display remarkable plasticity, yet the potential needs to be controlled in the context of multicellular organisms. We have revealed that a histone modifier PRC2 plays key roles in the maintenance of cellular differentiation status. In this study, I further studied how PRC2 prevents proliferation of terminally differentiated cells. I also found an example of mitotic re-entry and cellular de-differentiation of fully differentiated cells, when plants are exposed to wounding stress.
|