| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Previously, we isolated a decapeptide pheromone (sodefrin) from the abdominal glands of the male red-bellied newts (Cynops pyrrhogaster). Sodefrin plays an important role in keeping the female attracted to the male until the sperm transfer has been successfully completed.
In this study, endocrine regulations of the pheromone-responsive neurons were analyzed, and a novel peptide pheromone in sexually developed female was discovered. This pheromone has an activity to prompt the sexually developed males to commence courtship behavior toward the females. This is the first female sexual attractiveness peptide pheromone to be identified in a vertebrate. The finding of sex pheromones emitted by both reproductive male and female newts is expected to make it possible to analyze neural pathways and mechanisms involved in transferring the signals of both pheromones and transforming the pheromonal signals into the sexual behaviors in the newts of both sexes.
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