Research Project
Grant-in-Aid for Young Scientists (B)
Perception of microbe-associated molecular patterns by host cell-surface pattern recognition receptors triggers the intracellular activation of mitogen-activated protein kinase (MAPK) cascades. Plant bacterial pathogens generally deliver different effector proteins into plant cells. These effector proteins modulate the function of crucial host regulatory molecules and allow bacteria to invade plant cells. So far, we identified OsRLCK185 as interacting proteins of Xanthomonas effector, XopY.To understand the molecular mechanism of chitin-induced MAPK activation by OsRLCK185, we searched OsRLCK185 interactor and found MAPK kinase kinase OsMAPKKK18. Chitin-induced MAPK activation in the OsMAPKKK11/18 RNAi cells was clearly reduced compared with WT. Thus, it is likely that OsRLCK185 is the component that directly activates OsMAPKKK18 which triggers the activation of MAPK cascade after chitin perception.
All 2017 2016 2015
All Journal Article (3 results) (of which Int'l Joint Research: 1 results, Peer Reviewed: 3 results, Open Access: 1 results, Acknowledgement Compliant: 2 results) Presentation (8 results) (of which Int'l Joint Research: 4 results, Invited: 1 results)
Plant Cell Physiol
Volume: 印刷中 Issue: 6 Pages: 993-1002
10.1093/pcp/pcx042
The EMBO Journal
Volume: 35(22) Issue: 22 Pages: 2468-2483
10.15252/embj.201694248
バイオサイエンスとインダストリー
Volume: 73(3) Pages: 206-209
40020476222
