| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
DREB2A is a transcription factor that plays important roles in response to drought and heat stresses in Arabidopsis. While DREB2A is rapidly degraded under normal conditions, it is stabilized in response to these stresses to activate expression of downstream stress-responsive genes. However, the mechanism underlying the conditional changes of DREB2A stability in response to stresses remains to be elucidated.
In this study, we found that stress-dependent change of DREB2A phosphorylation enables stability regulation according to environmental changes. As an important sequence motif for phosphorylation is functionally conserved among angiosperms, similar regulatory mechanisms is expected to function in other angiosperms.
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