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Is Reston ebolavirus an Asian virus? - Epidemiological investigation in Southern Africa

Research Project

Project/Area Number 15K18777
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Veterinary medical science
Research InstitutionOkayama University

Principal Investigator

Ogawa Hirohito  岡山大学, 医歯薬学総合研究科, 助教 (80455237)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsエボラウイルス / レストンエボラウイルス / フィロウイルス / ブタ / ザンビア共和国 / アフリカ / 人獣共通感染症 / 血清疫学
Outline of Final Research Achievements

Ebolavirus causes severe hemorrhagic fever. Reston ebolavirus which is one of ebolavirus species has thus far been found only in Asia. Our previous serological surveillance of filoviruses in fruit bats migrating to Zambia suggested that Reston ebolavirus or Reston-like virus existed in Africa. In this study, we carried out a serological survery to detect Reston ebolavirus-specific IgG antibodies in pig, which is suspected to be one of natural hosts, in Zambia. A total of 1082 swine serum samples were screened for IgG antibodies specific to the Reston ebolavirus by ELISA method, and the OD values obtained were analyzed statistically. Ten samples were found to be IgG positive, suggesting that Reston ebolavirus or Reston-like virus have been introduced into the pig population in Zambia.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (8 results)

All 2018 2017 2016 Other

All Int'l Joint Research (3 results) Journal Article (2 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Int'l Joint Research] ザンビア大学獣医学部/Central Veterinary Research Institute(ザンビア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] ザンビア大学獣医学部/Central Veterinary Research Institute(ザンビア)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] ザンビア大学獣医学部/Central Veterinary Research Institute(ザンビア)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Characterization of a Novel Bat Adenovirus Isolated from Straw-Colored Fruit Bat (Eidolon helvum)2017

    • Author(s)
      Ogawa Hirohito、Kajihara Masahiro、Nao Naganori、Shigeno Asako、Fujikura Daisuke、Hang’ombe Bernard、Mweene Aaron、Mutemwa Alisheke、Squarre David、Yamada Masao、Higashi Hideaki、Sawa Hirofumi、Takada Ayato
    • Journal Title

      Viruses

      Volume: 9 Issue: 12 Pages: 371-371

    • DOI

      10.3390/v9120371

    • NAID

      120006382305

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Co-circulation of multiple genotypes of African swine fever viruses among domestic pigs in Zambia (2013-2015).2017

    • Author(s)
      Simulundu E, Chambaro HM, Sinkala Y, Kajihara M, Ogawa H, Mori A, Ndebe J, Dautu G, Mataa L, Lubaba CH, Simuntala C, Fandamu P, Simuunza M, Pandey GS, Samui KL, Misinzo G, Takada A, Mweene AS
    • Journal Title

      Transbound Emerg Dis

      Volume: - Issue: 1 Pages: 114-122

    • DOI

      10.1111/tbed.12635

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] フィロウイルスの自然宿主は?-ザンビアでオオコウモリを追う-2018

    • Author(s)
      小川寛人
    • Organizer
      第233回アフリカ地域研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Seroepidemiological Prevalence of Multiple Species of Filoviruses in Fruit Bats (Eidolon helvum and Rousettus aegyptiacus) in Zambia2016

    • Author(s)
      Kajihara M, Ogawa H, Miyamoto H, Changula K, Qiu Y, Mori A, Yoshida R, Thomas Y, Nakagawa E, Hang’ombe B, Simulundu E, Muleya W, Katampi J, Igarashi M, Moonga L, Ndebe J, Kapila P, Mweene A, Takada A
    • Organizer
      8th International Symposium on Filoviruses
    • Place of Presentation
      Antwerp, Belgium
    • Year and Date
      2016-09-12
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] ザンビア共和国に飛来するストローオオコウモリ(Eidolon helvum)から分離されたアデノウイルスの性状解析と分子疫学的解析2016

    • Author(s)
      小川寛人,梶原将大,直亨則,丸山隼輝,上野恵介,石井秋宏,藤倉大輔,Hang’ombe Bernard, Aaron Mweene, 山田雅夫,東秀明,澤洋文,高田礼人
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      藤沢市
    • Year and Date
      2016-09-06
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2022-10-20  

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