Research for pathogenic and potentially pathogenic viruses in Zambia

• Project/Area Number: 15K18778
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Veterinary medical science
• Research Institution: Hokkaido University
• Principal Investigator: Kajihara Masahiro 北海道大学, 人獣共通感染症リサーチセンター, 特任助教 (70711894)
• Project Period (FY): 2015-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 人獣共通感染症 / ウイルス / 出血熱 / マダニ / コウモリ / ザンビア / アフリカ / マールブルグウイルス / フィロウイルス / エボラウイルス / クリミア・コンゴ出血熱 / フレボウイルス / ダニ媒介性ウイルス / ダニ / 新興感染症 / ウイルス性出血熱

Outline of Final Research Achievements

In this study, epidemiological and ecological survey for known and unknown viruses was carried out in Zambia to understand ecology of these viruses and evaluate their risk for public health in the southern African region . During the research period, 2,327 ticks and 919 bats were sampled in Zambia. By genetic screening using RT-PCR, Crimean-Congo hemorrhagic fever virus was detected in Hyalomma ticks. Marburgvirus genome was also detected in cave-dwelling Egyptian fruit bats captured in September 2018. These viruses are known to cause viral hemorrhagic fevers in humans. In addition, tick-borne phleboviruses were also detected. Phylogenetic analysis revealed that these tick-borne phleboviruses were grouped into 8 distinct clusters including most likely novel genetic lineages. Bat mumpsvirus in the family Paramyxoviridae was also isolated from an Epomophorus sp. bat.

Academic Significance and Societal Importance of the Research Achievements

本研究で検出されたCCHFVおよびマールブルグウイルスは共にヒトに対して致死的な出血熱を引き起こすことで知られている。過去、ザンビアにおいてこれらのウイルスによる感染症が発生したことはなく、その存在を示す研究データも存在しなかった。本研究を通して、ザンビアにもこれらの出血熱ウイルスが存在することが初めて示唆された。本研究の成果は同国のみならず、南部アフリカ地域における公衆衛生において非常に重要な知見を提供するものである。

Research Products

• [Int'l Joint Research] ザンビア大学 獣医学部/大学教育病院/国立公園・野生動物管理局(ザンビア)
• [Int'l Joint Research] ザンビア大学獣医学部/ザンビア大学教育病院/中央獣医研究所(ザンビア)
• [Int'l Joint Research] 国立生物医学研究所(コンゴ民主共和国)
• [Int'l Joint Research] ザンビア大学獣医学部/ザンビア大学教育病院/中央獣医研究所(ザンビア)
• [Int'l Joint Research] 国立生医科学研究所(コンゴ民主共和国)
• [Int'l Joint Research] ザンビア大学獣医学部/ザンビア大学教育病院/中央獣医研究所(ザンビア)
• [Journal Article] Diversity of spotted fever group rickettsiae and their association with host ticks in Japan (2019)
  • Author(s): Thu MJ, Qiu Y, Matsuno K, Kajihara M, Mori-Kajihara A, Omori R, Monma N, Chiba K, Seto J, Gokuden M, Andoh M, Oosako H, Katakura K, Takada A, Sugimoto C, Isoda N, Nakao R
  • Journal Title: Scientific Reports Volume: 9(1) Issue: 1 Pages: 1500-1500
  • DOI: 10.1038/s41598-018-37836-5
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Infection of newly identified phleboviruses in ticks and wild animals in Hokkaido, Japan indicating tick-borne life cycles (2019)
  • Author(s): Torii Shiho、Matsuno Keita、Qiu Yongjin、Mori-Kajihara Akina、Kajihara Masahiro、Nakao Ryo、Nao Naganori、Okazaki Katsunori、Sashika Mariko、Hiono Takahiro、Okamatsu Masatoshi、Sakoda Yoshihiro、Ebihara Hideki、Takada Ayato、Sawa Hirofumi
  • Journal Title: Ticks and Tick-borne Diseases Volume: 10 Issue: 2 Pages: 328-335
  • DOI: 10.1016/j.ttbdis.2018.11.012
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Human Borreliosis Caused by a New World Relapsing Fever Borrelia-like Organism in the Old World (2018)
  • Author(s): Qiu Yongjin、Nakao Ryo、Hang’ombe Bernard Mudenda、Sato Kozue、Kajihara Masahiro、Kanchela Sharon、Changula Katendi、Eto Yoshiki、Ndebe Joseph、Sasaki Michihito、Thu May June、Takada Ayato、Sawa Hirohumi、Sugimoto Chihiro、Kawabata Hiroki
  • Journal Title: Clinical Infectious Diseases Volume: 印刷中 Issue: 1 Pages: 107-112
  • DOI: 10.1093/cid/ciy850
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The Unique Phylogenetic Position of a Novel Tick-Borne Phlebovirus Ensures an Ixodid Origin of the Genus Phlebovirus (2018)
  • Author(s): Matsuno Keita、Kajihara Masahiro、Nakao Ryo、Nao Naganori、Mori-Kajihara Akina、Muramatsu Mieko、Qiu Yongjin、Torii Shiho、Igarashi Manabu、Kasajima Nodoka、Mizuma Keita、Yoshii Kentaro、Sawa Hirofumi、Sugimoto Chihiro、Takada Ayato、Ebihara Hideki
  • Journal Title: mSphere Volume: 3 Issue: 3
  • DOI: 10.1128/msphere.00239-18
  • NAID: 120006501204
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Seroprevalence of Filovirus Infection of Rousettus aegyptiacus Bats in Zambia (2018)
  • Author(s): Changula K, Kajihara M, Mori-Kajihara A, Eto Y, Miyamoto H, Yoshida R, Shigeno A, Hang'ombe B, Qiu Y, Mwizabi D, Squarre D, Ndebe J, Ogawa H, Harima H, Simulundu E, Moonga L, Kapila P, Furuyama W, Kondoh T, Sato M, Takadate Y, Kaneko C, Nakao R, Mukonka V, Mweene A, Takada A
  • Journal Title: J Infect Dis Volume: 218(Suppl 5)
  • DOI: 10.1093/infdis/jiy266
  • NAID: 120006771013
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Molecular detection and characterization of zoonotic Anaplasma species in domestic dogs in Lusaka, Zambia (2018)
  • Author(s): Vlahakis Pipina、Chitanga Simbarashe、Simuunza Martin、Simulundu Edgar、Qiu Yongjin、Changula Katendi、Chambaro Herman、Kajihara Masahiro、Nakao Ryo、Takada Ayato、Mweene Aaron
  • Journal Title: Ticks and Tick-borne Diseases Volume: 9 Issue: 1 Pages: 39-43
  • DOI: 10.1016/j.ttbdis.2017.10.010
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] First molecular detection and genetic characterization of Coxiella burnetii in Zambian dogs and rodents (2018)
  • Author(s): Chitanga Simbarashe、Simulundu Edgar、Simuunza Martin、Changula Katendi、Qiu Yongjin、Kajihara Masahiro、Nakao Ryo、Syakalima Michelo、Takada Ayato、Mweene S Aaron、Mukaratirwa Samson、Hang’ombe Bernard
  • Journal Title: Parasites & Vectors Volume: 11 Issue: 1 Pages: 40-40
  • DOI: 10.1186/s13071-018-2629-7
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] normal Expression of a Recombinant Nucleocapsid Protein of Rift Valley Fever Virus in Vero Cells as an Immunofluorescence Antigen and Its Use for Serosurveillance in Traditional Cattle Herds in Zambia (2018)
  • Author(s): Saasa Ngonda、Kajihara Masahiro、Dautu George、Mori-Kajihara Akina、Fukushi Shuetsu、Sinkala Yona、Morikawa Shigeru、Mweene Aaron、Takada Ayato、Yoshimatsu Kumiko、Arikawa Jiro
  • Journal Title: Vector-Borne and Zoonotic Diseases Volume: 印刷中 Issue: 5 Pages: 273-277
  • DOI: 10.1089/vbz.2017.2186
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Tick-borne haemoparasites and Anaplasmataceae in domestic dogs in Zambia (2018)
  • Author(s): Qiu Yongjin、Kaneko Chiho、Kajihara Masahiro、Ngonda Saasa、Simulundu Edgar、Muleya Walter、Thu May J、Hang’ombe Bernard、Katakura Ken、Takada Ayato、Sawa Hirofumi、Simuunza Martin、Nakao Ryo
  • Journal Title: Ticks and Tick-borne Diseases Volume: 印刷中 Issue: 4 Pages: 988-995
  • DOI: 10.1016/j.ttbdis.2018.03.025
  • NAID: 120006626572
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genetic characterization of orf virus associated with an outbreak of severe orf in goats at a farm in Lusaka, Zambia (2015) (2017)
  • Author(s): Simulundu Edgar、Mtine Nandi、Kapalamula Thoko、Kajihara Masahiro、Qiu Yongjin、Ngoma James、Zulu Victor、Kwenda Geoffrey、Chisanga Chrispin、Phiri Isaac、Takada Ayato、Mweene Aaron
  • Journal Title: Archives of Virology Volume: 162 Issue: 8 Pages: 2363-2367
  • DOI: 10.1007/s00705-017-3352-y
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The Epidemiology of African Swine Fever in “Nonendemic” Regions of Zambia (1989?2015): Implications for Disease Prevention and Control (2017)
  • Author(s): Simulundu Edgar、Lubaba Caesar、van Heerden Juanita、Kajihara Masahiro、Mataa Liywalii、Chambaro Herman、Sinkala Yona、Munjita Samuel、Munang’andu Hetron、Nalubamba King、Samui Kenny、Pandey Girja、Takada Ayato、Mweene Aaron
  • Journal Title: Viruses Volume: 9 Issue: 9 Pages: 236-236
  • DOI: 10.3390/v9090236
  • NAID: 120006410538
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Putative endogenous filovirus VP35-like protein potentially functions as an IFN antagonist but not a polymerase cofactor (2017)
  • Author(s): Kondoh Tatsunari、Manzoor Rashid、Nao Naganori、Maruyama Junki、Furuyama Wakako、Miyamoto Hiroko、Shigeno Asako、Kuroda Makoto、Matsuno Keita、Fujikura Daisuke、Kajihara Masahiro、Yoshida Reiko、Igarashi Manabu、Takada Ayato
  • Journal Title: PLOS ONE Volume: 12 Issue: 10 Pages: e0186450-e0186450
  • DOI: 10.1371/journal.pone.0186450
  • NAID: 120006366507
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characterization of a Novel Bat Adenovirus Isolated from Straw-Colored Fruit Bat (Eidolon helvum) (2017)
  • Author(s): Ogawa Hirohito、Kajihara Masahiro、Nao Naganori、Shigeno Asako、Fujikura Daisuke、Hang’ombe Bernard、Mweene Aaron、Mutemwa Alisheke、Squarre David、Yamada Masao、Higashi Hideaki、Sawa Hirofumi、Takada Ayato
  • Journal Title: Viruses Volume: 9 Issue: 12 Pages: 371-371
  • DOI: 10.3390/v9120371
  • NAID: 120006382305
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Co-circulation of multiple genotypes of African swine fever viruses among domestic pigs in Zambia (2013-2015). (2017)
  • Author(s): Simulundu E, Chambaro HM, Sinkala Y, Kajihara M, Ogawa H, Mori A, Ndebe J, Dautu G, Mataa L, Lubaba CH, Simuntala C, Fandamu P, Simuunza M, Pandey GS, Samui KL, Misinzo G, Takada A, Mweene AS
  • Journal Title: Transbound Emerg Dis Volume: - Issue: 1 Pages: 114-122
  • DOI: 10.1111/tbed.12635
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genetic predisposition to acquire a polybasic cleavage site for highly pathogenic avian influenza virus hemagglutinin (2017)
  • Author(s): Nao N, Yamagishi J, Miyamoto H, Igarashi M, Manzoor R, Ohnuma A, Tsuda Y, Furuyama W, Shigeno A, Kajihara M, Kishida N, Yoshida R, Takada A
  • Journal Title: MBio Volume: 8 Issue: 1 Pages: 1-15
  • DOI: 10.1128/mbio.02298-16
  • NAID: 120006337761
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Clinical and subclinical bovine leukemia virus infection in a dairy cattle herd in Zambia (2017)
  • Author(s): Pandey GS, Simulundu E, Mwiinga D, Samui KL, Mweene AS, Kajihara M, Mangani A, Mwenda R, Ndebe J, Konnai S, Takada A.
  • Journal Title: Arch Virol. Volume: 162(4) Issue: 4 Pages: 1051-1056
  • DOI: 10.1007/s00705-016-3205-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Putative RNA viral sequences detected in an Ixodes scapularis-derived cell line. (2016)
  • Author(s): Nakao R, Matsuno K, Qiu Y, Maruyama J, Eguchi N, Nao N, Kajihara M, Yoshii K, Sawa H, Takada A, Sugimoto C.
  • Journal Title: Ticks Tick Borne Dis. Volume: 8 Issue: 1 Pages: 103-111
  • DOI: 10.1016/j.ttbdis.2016.10.005
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Development of an Immunochromatography Assay (QuickNavi-Ebola) to Detect Multiple Species of Ebolaviruses (2016)
  • Author(s): Yoshida R, Muramatsu S, Akita H, Saito Y, Kuwahara M, Kato D, Changula K, Miyamoto H, Kajihara M, Manzoor R, Furuyama W, Marzi A, Feldmann H, Mweene A, Masumu J, Kapeteshi J, Muyembe-Tamfum JJ, Takada A
  • Journal Title: The Journal of Infectious Diseases Volume: 214(suppl 3) Issue: suppl 3 Pages: S185-S191
  • DOI: 10.1093/infdis/jiw252
  • NAID: 120006352204
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] A Single Amino Acid in the M1 Protein Responsible for the Different Pathogenic Potentials of H5N1 Highly Pathogenic Avian Influenza Virus Strains (2015)
  • Author(s): Nao N, Kajihara M, Manzoor R, Maruyama J, Yoshida R, Muramatsu M, Miyamoto H, Igarashi M, Eguchi N, Sato M, Kondoh T, Okamatsu M, Sakoda Y, Kida H, Takada A
  • Journal Title: PLoS One Volume: 10(9) Issue: 9 Pages: e0137989-e0137989
  • DOI: 10.1371/journal.pone.0137989
  • NAID: 120005672370
  • Peer Reviewed / Open Access
• [Journal Article] The Interaction between TIM-1 and NPC1 is important for the cellular entry of Ebola virus (2015)
  • Author(s): Kuroda M, Fujikura D, Nanbo A, Marzi A, Noyori O, Kajihara M, Maruyama J, Matsuno K, Miyamoto H, Yoshida R, Feldmann H, Takada A
  • Journal Title: J. Virol. Volume: 印刷中 Issue: 12 Pages: 6481-6493
  • DOI: 10.1128/jvi.03156-14
  • NAID: 120005621883
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Seroepidemiological prevalence of multiple species of filoviruses in fruit bats (Eidolon helvum) migrating in Africa. (2015)
  • Author(s): Hirohito Ogawa, Hiroko Miyamoto, Eri Nakayama, Reiko Yoshida, Ichiro Nakamura, Hirofumi Sawa, Akihiro Ishii, Yuka Thomas, Emiko Nakagawa, Keita Matsuno, Masahiro Kajihara, Junki Maruyama, Manabu Igarashi, Kimihito Ito, Ayato Takada et al
  • Journal Title: Journal of Infectious Diseases Volume: jiv063 Issue: suppl 2 Pages: S101-S108
  • DOI: 10.1093/infdis/jiv063
  • Peer Reviewed / Open Access
• [Presentation] Seroprevalence of filovirus infection of Rousettus aegyptiacus bats in Zambia (2018)
  • Author(s): Kajihara M, Changula K, Mori-Kajihara A, Eto Y, Miyamoto H, Yoshida R, Shigeno A, Hang'ombe B M, Qiu Y, Mwizabi D, Squarre D, Ogawa H, Harima H, Simulundu E, Kondoh T, Sato M, Takadate Y, Mukonka V, Mweene A S, Takada A
  • Organizer: The 66th Annual Meeting of the Japanese Society for Virology
• [Presentation] Characterization of a novel bat adenovirus isolated from straw-colored fruit bat (Eidolon helvum) (2018)
  • Author(s): Ogawa H, Kajihara M, Nao N, Shigeno A, Fujikura D, Hang'ombe B M, Mweene A S, Mutemwa A, Squarre D, Yamada M, Higashi H, Sawa H, Takada A
  • Organizer: The 66th Annual Meeting of the Japanese Society for Virology
• [Presentation] Serological and molecular evidence for Crimean-Congo hemorrhagic fever virus circulation in ticks, cattle, and humans in Zambia (2018)
  • Author(s): Kajihara M, Simuunza M, Mori-Kajihara A, Saasa N, Qiu Y, Eto Y, Nakao R, Dautu G, Hang'ombe B, Orba Y, Sawa H, Fukushi S, Morikawa S, Saijo M, Arikawa J, Mweene A, Monze M, Mukonka V, Takada A, Yoshimatsu K
  • Organizer: 2018 Negative Strand RNA Virus Meeting
  • Int'l Joint Research
• [Presentation] Surveillance of Viral Zoonoses in Africa (2018)
  • Author(s): Mweene Aaron、Kajihara Masahiro、Inano Koichi、Takada Ayato
  • Organizer: Prince Mahidol Award Conference 2018
  • Int'l Joint Research / Invited
• [Presentation] Discoveries of novel viruses in ticks and fruit bats by using FLDS method and MinION sequencer (2017)
  • Author(s): Matsuno Keita、Kajihara Masahiro、Urayama Syun-Ichi、Nakao Ryo、Hirai Miho、Qiu Yongjin、Nunoura Takuro、Mweene Aaron、Hang'ombe Bernard、Simuunza Martin、Okamatsu Masatoshi、Sakoda Yoshihiro、Sawa Hirofumi、Takada Ayato
  • Organizer: 第65回 日本ウイルス学会学術集会
• [Presentation] Functional analyses of endogenous ebolavirus VP35-like element (2017)
  • Author(s): Kondoh Tatsunari、Manzoor Rashid、Nao Naganori、Maruyama Junki、Furuyama Wakako、Miyamoto Hiroko、Shigeno Asako、Kuroda Makoto、Matsuno Keita、Fujikura Daisuke、Kajihara Masahiro、Yoshida Reiko、Igarashi Manabu、Takada Ayato
  • Organizer: 第65回 日本ウイルス学会学術集会
• [Presentation] Discovery of genetically diverse phleboviruses in ticks in Zambia (2017)
  • Author(s): Kajihara Masahiro、Simuunza Martin、Nakao Ryo、Mori Akina、Qiu Yongjin、Eto Yoshiki、Matsuno Keita、Furumoto Hayato、Kapila Penjaninge、Dautu George、Mweene Aaron、Takada Ayato
  • Organizer: 9th Tick and Tick Borne Pathogen Conference and1st Asia Pacific Rickettsia Conference
  • Int'l Joint Research
• [Presentation] Serological and molecular epidemiology of Crimean-Congo hemorrhagic fever in Zambia (2017)
  • Author(s): Simuunza Martin、Kajihara Masahiro、Mori Akina、Dautu George、Qiu Yongjin、Nakao Ryo、Eto Yoshiki、Saasa Ngonda、Furumoto Hayato、Fukushi Shuetsu、Morikawa Shigeru、Saijo Masayuki、Yoshimatsu Kumiko、Mweene Aaron、Takada Ayato、Arikawa Jiro
  • Organizer: 9th Tick and Tick Borne Pathogen Conference and1st Asia Pacific Rickettsia Conference
  • Int'l Joint Research
• [Presentation] Investigation of tick-borne bacterial and protozoan pathogens in domestic dogs, cattle, and ticks in Zambia (2017)
  • Author(s): Qiu Yongjin、Kaneko Chiho、Kajihara Masahiro、Simuunza Martin、Saasa Ngonda、Furumoto Hayato、Ndebe Joseph、Kapila Penjani、June Thu May、Hang’ombe Bernard、Takada Ayato、Sugimoto Chihiro、Nakao Ryo
  • Organizer: 9th Tick and Tick Borne Pathogen Conference and1st Asia Pacific Rickettsia Conference
  • Int'l Joint Research
• [Presentation] Filovirus surveillance in Rousettus aegyptiacus bats in Zambia (2017)
  • Author(s): Changula Katendi、Kajihara Masahiro、Miyamoto Hiroko、Hang'ombe Bernard、Mori Akina、Qiu Yongjin、Eto Yoshiki、Simulundu Edgar、Ndebe Joseph、Shigeno Asako、Ogawa Hirohito、Moonga Ladslav、Kapila Penjaninge、Mweene Aaron、Takada Ayato
  • Organizer: 9th International Symposium on Filoviruses
  • Int'l Joint Research
• [Presentation] Surveillance of Viral Zoonoses in Africa (2017)
  • Author(s): Takada A、Kajihara M、Mori A、Yoshida R、Miyamoto H、Igarashi M、Sawa H、Orba Y、Nakamura I、Isoda N、Ishii A、Ito K、Arikawa J、Yoshimatsu K、Ogawa H、Simulundu E、Changula K、Saasa N、Muleya W、Yabe J、Munyeme M、Hang'ombe B、Simuunza M、Choongo K、Mweene A
  • Organizer: The 2nd International Joint Symposium: Promotion of Infectious Disease Research Cooperation between Africa and Japan toward Science, Technology and Innovation
  • Int'l Joint Research / Invited
• [Presentation] Recombinant expressed nucleoprotein protein of Rift Valley fever virus and sero-surveillance in traditional cattle herds in Zambia (2016)
  • Author(s): Saasa N, Kajihara M, Dautu G, Morikawa S, Saijo M, Takada A, Mweene A, Yoshimatsu K, Arikawa J
  • Organizer: 第64回日本ウイルス学会学術集会
  • Place of Presentation: 札幌コンベンションセンター (北海道・札幌市)
  • Year and Date: 2016-10-23
• [Presentation] Genetic diversity of rabies virus circulating in different hosts and regions in Zambia and Zimbabwe (2016)
  • Author(s): Muleya W, Chambaro H, Kajihara M, Saasa N, Mori A, Qiu Y, Sasaki M, Gwenhure L, Mweene A, Namangala B, Takada A, Sawa H
  • Organizer: 第64回日本ウイルス学会学術集会
  • Place of Presentation: 札幌コンベンションセンター (北海道・札幌市)
  • Year and Date: 2016-10-23
• [Presentation] Involvement of multiple genotypes of African swine fever viruses during 2013-2015 outbreaks in Zambia (2016)
  • Author(s): Simulundu E, Chambaro H, Kajihara M, Ogawa H, Mori A, Ndebe J, Mataa L, Lubaba C, Simuntala C, Dautu G, Misinzo G, Takada A, Mweene A
  • Organizer: 第64回日本ウイルス学会学術集会
  • Place of Presentation: 札幌コンベンションセンター (北海道・札幌市)
  • Year and Date: 2016-10-23
• [Presentation] Genetic predisposition to acquire a polybasic cleavage site for highly pathogenic avian influenza virus hemagglutinin/インフルエンザウイルスヘマグルチニン開裂部位への塩基性アミノ酸挿入のメカニズム解析 (2016)
  • Author(s): Nao N, Yamagishi J, Miyamoto H, Igarashi M, Manzoor R, Ohnuma A, Tsuda Y, Furuyama W, Kajihara M, Yoshida R, Takada A
  • Organizer: 第64回日本ウイルス学会学術集会
  • Place of Presentation: 札幌コンベンションセンター (北海道・札幌市)
  • Year and Date: 2016-10-23
• [Presentation] Seroepidemiological Prevalence of Multiple Species of Filoviruses in Fruit Bats (Eidolon helvum and Rousettus aegyptiacus) in Zambia (2016)
  • Author(s): Kajihara M, Ogawa H, Miyamoto H, Changula K, Qiu Y, Mori A, Yoshida R, Thomas Y, Nakagawa E, Hang’ombe B, Simulundu E, Muleya W, Katampi J, Igarashi M, Moonga L, Ndebe J, Kapila P, Mweene A, Takada A
  • Organizer: 8th International Symposium on Filoviruses
  • Place of Presentation: Institute of Tropical Medicine (Antwerp, Belgium)
  • Year and Date: 2016-09-12
• [Presentation] Development of an immunochromatography rapid kit for Ebola virus antigen/エボラウイルス抗原検出迅速診断キットの開発 (2015)
  • Author(s): Yoshida R, Muramatsu S, Akita H, Saito Y, Kuwahara M, Kato D, Katendi C, Miyamoto H, Kajihara M, Takada A.
  • Organizer: 第63回日本ウイルス学会学術集会
  • Place of Presentation: 福岡国際会議場（福岡県・福岡市）
  • Year and Date: 2015-11-22
• [Presentation] Genetic divergence of phleboviruses newly identified in ticks collected in Japan, Zambia and the United States/日本国内外のマダニにみられるフレボウイルスの遺伝的多様性 (2015)
  • Author(s): Matsuno K, Shimoda H, Torii S, Yongjin Q, Brandi W, Nakao R, Kajihara M, Okamatsu M, Sakoda Y, Okumura A, Takada A, Tom S, Maeda K, Ebihara H.
  • Organizer: 第63回日本ウイルス学会学術集会
  • Place of Presentation: 福岡国際会議場（福岡県・福岡市）
  • Year and Date: 2015-11-22
• [Book] 臨床とウイルス 45/1 2017年3月号 (2017)
  • Author(s): 梶原将大、髙田礼人
  • Publisher: 日本臨床ウイルス学会
• [Book] 生体の科学 第66巻第4号 (2015)
  • Author(s): 梶原将大、高田礼人
  • Total Pages: 5
  • Publisher: 医学書院
• [Book] 実験医学 第33巻第8号 (2015)
  • Author(s): 梶原将大
  • Total Pages: 3
  • Publisher: 羊土社
• [Remarks] 北海道大学 人獣共通感染症リサーチセンター 国際疫学部門 研究内容
  • URL: http://www.czc.hokudai.ac.jp/epidemiol/research/
• [Remarks] 北海道大学 人獣共通感染症リサーチセンター 国際疫学部門 研究内容
  • URL: http://www.czc.hokudai.ac.jp/epidemiol/research/