New Entries to Ring Construction Based on Cycloaddition between Allenyl Bonds and C-C Multiple Bonds
| Project/Area Number |
15K18826
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | アレン / C-H活性化 / アルキン / アルケン / ロジウム / 環化反応 / C-C活性化 / 環構築反応 / ロジウム触媒 |
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| Outline of Final Research Achievements |
In line with the initial plan, (1) development of a cycloisomerization of allene-alkynes via a C-H bond activation, and (2) development of an asymmetric intramolecular [2+2+2] cycloaddition of allene-ene-ynes were attempted. In the study of (1), we were able to develop the planned reaction. In the study of (2), we could not obtain the originally intended results, but succeeded in developing a new cyclization reaction different from the intended reaction. Furthermore, we were able to develop the following two ring-closing reactions in the relevant region, namely the partially intermolecular [2+2+2] cycloaddition of allene-alkynes with alkynes, and the intramolecular [6+2] cycloaddition of allenylazacyclobutane-alkynes.
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Report
(3 results)
Research Products
(19 results)
