Helical chirality of helicene that creates an effective asymmetric reaction field?
| Project/Area Number |
15K18835
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | ヘリセン / 不斉リン配位子 / Miyazaki-Newman-Kwart転位 / 硫黄官能基化ヘリセン / 光学分割 / チアヘリセン / 不斉触媒 / ヘリセンチオール / [7]チアヘリセン / ホスフィナイト / 不斉配位子 / パラジウム / 不斉アリル位アルキル化 |
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| Outline of Final Research Achievements |
In this study, a helicene-based phosphinite ligands has been synthesized and its catalytic activity has been evaluated using the model reaction. Furthermore, the synthesis and optical resolution of helically chiral 1-sulfur-functionalized [6]helicene have been accomplished. A novel enantiopure [7]thiahelicene has also been synthesized.
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Report
(3 results)
Research Products
(6 results)
