Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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Outline of Final Research Achievements |
In this study, we clarified a treatment strategy for oral mucositis caused by chemo- and radio-therapy in cancer patients. Briefly, we used the 0.25% of indomethacin solution to the mucositis in the oral cavity of 28 cancer patients with oral mucositis. The pain relief was obtained 26 out of 28 (93%) in this study. The absorption of indomethacin after applying indomethacin oral spray in 7 cancer patients was found comparable to the topical indomethacin agents such as patch or lotion. In conclution, we found the indometahcin oral spray was safe and effective in the patients with oral mucositis.
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