Evaluation of pain caused by lumbar canal stenosis using functional MRI

• Project/Area Number: 15K19192
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pain science
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: Mizuno Kentaro 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 (10725675)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: ｆMRI / fMRI / 痛みの可視化 / 腰部脊柱管狭窄症

Outline of Final Research Achievements

Intermittent claudication caused by lumbar canal stenosi is one of the difficult pain to manage. There are no good method to evaluate pain objectively.In this study, we tried to visualize the intensity of pain caused by lumbar canal stenosis using functional MRI(fMRI).We developed lumar canal stenosis model rats and stimulate their planta durinf fMRI scannning. Signal intensity in some rats' brain are diffrent from noramal rat ones. More research are required to know more about pain. We will arrange conditions during scanning fMRI scanning