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Developmemnt of high precision dose calculation system using Quantitative Susceptibility Mapping

Research Project

Project/Area Number 15K19198
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Research InstitutionTohoku University

Principal Investigator

Ito Kengo  東北大学, 大学病院, 助手 (40705076)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords定量的磁化率マッピング / MRI-based RTP / MRI-Linac / MRI--based RTP / 磁気共鳴断層撮像装置 / X線断層撮像装置
Outline of Final Research Achievements

Accurate evaluation of the relative electron density (rED) from MRI will enable treatment planning based on MR images alone. The aim of this study was to develop radiotherapy treatment planning method using magnetic susceptibility obtained from Quantitative Susceptibility Mapping (QSM) via MR imaging. This study demonstrates the feasibility of the method for generating an MRI substitute for a CT images. A correlation between magnetic susceptibility and rED was not observed using our proposed method. In contrast to the magnetic susceptibility values obtained from the QSM algorithm, which were strongly affected by calcification and iron content, the rED was not considerably affected by such materials.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Feasibility of a Direct-Conversion Method from Magnetic Susceptibility to Relative Electron Density for Radiation Therapy Treatment Planning2017

    • Author(s)
      Ito Kengo、Kadoya Noriyuki、Nakajima Yujiro、Saito Masahide、Sato Kiyokazu、Nagasaka Tatsuo、Yamanaka Kazuomi、Dobashi Suguru、Takeda Ken、Matsushita Haruo、Jingu Keiichi
    • Journal Title

      International Journal of Medical Physics, Clinical Engineering and Radiation Oncology

      Volume: 06 Issue: 03 Pages: 252-265

    • DOI

      10.4236/ijmpcero.2017.63023

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Feasibility of Magnetic Susceptibility to Relative Electron Density Conversion Method for Radiation Therapy2016

    • Author(s)
      Kengo Ito
    • Organizer
      AAPM 58th Annual Meeting
    • Place of Presentation
      Washington, USA
    • Year and Date
      2016-07-31
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Feasibility of Magnetic Susceptibility to Relative Electron Density Conversion Table for Radiation Therapy2016

    • Author(s)
      Kengo Ito
    • Organizer
      The American Association of Physicists in Medicine
    • Place of Presentation
      Washington,DC
    • Year and Date
      2016-07-31
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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