Patient setup system using a virtual X-ray image

• Project/Area Number: 15K19212
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical Physics and Radiological Technology
• Research Institution: Japanese Foundation for Cancer Research
• Principal Investigator: Hashimoto Masatoshi 公益財団法人がん研究会, 有明病院 放射線治療部, 医学物理士 (40375845)
• Co-Investigator(Renkei-kenkyūsha): HAGA Akihiro 東京大学, 医学部附属病院, 助教 (30448021) ; NAWA Kanabu 東京大学, 医学部附属病院, 助教 (00456914) ; NAKANO Masahiro がん研究会, 放射線治療部, 医学物理士 (50780384) ; TAKAHASHI Ryo がん研究会, 放射線治療部, 診療放射線技師 (10716757) ; MATSUBAYASHI Fumiyasu がん研究会, 放射線治療部, 診療放射線技師 (60716760) ; ITO Yasushi がん研究会, 放射線治療部, 診療放射線技師 (90627564) ; KOZUKA Takuyo がん研究会, 放射線治療部, 副部長 (30300932) ; OGUCHI Masahiko がん研究会, 放射線治療部, 部長 (50169257)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 放射線治療 / 外部照射 / 患者セットアップ / 距離画像センサ

Outline of Final Research Achievements

This study aimed to build a system to generate virtual X-ray images of patient position at the time of radiotherapy based on skinned mesh animation from depth images and skeleton data acquired by a range imaging sensor. We constructed a system to generate a virtual X-ray image which can be directly compared with digitally reconstructed radiograph (DRR) in real time using a range imaging sensor and treatment planning computed tomography images. In order to improve the accuracy of the virtual X-ray image, it is necessary to improve the reproducibility of the skeleton data and the detection accuracy of the depth image. This system enables highly accurate and non-invasive patient setup, and will lead to safer and more accurate radiotherapy.

Research Products

• [Journal Article] A Half-Arc Multiple Deep-Inspiration Breath-Hold Volumetric Modulated Arc Therapy for a Lung Tumor with 10 MV Flattening-Filter-Free Beams and an Image Sensor Measuring a Distance Map to Thorax Surface: An Initial Clinical Experience (2017)
  • Author(s): Keiichi Nakagawa, Kanabu Nawa, Masatoshi Hashimoto, Shuri Aoki, Yoshihiro Kaneko, Hideomi Yamashita, Akihiro Haga
  • Journal Title: International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Volume: 6 Issue: 01 Pages: 31-35
  • DOI: 10.4236/ijmpcero.2017.61004
  • Peer Reviewed / Open Access
• [Journal Article] Acute and late complications after hypofractionated intensity modulated radiotherapy in prostate cancer (2017)
  • Author(s): Kozuka T, Nakano M, Hashimoto M, Gomi K, Murofushi K, Sumi M, Yonese J, Oguchi M
  • Journal Title: Japanese Journal of Radiology Volume: 35 Issue: 5 Pages: 269-278
  • DOI: 10.1007/s11604-017-0630-2
  • NAID: 50012595360
  • Peer Reviewed
• [Presentation] Four-dimensional dose reconstruction for lung cancer in volumetric modulated arc therapy (2016)
  • Author(s): Masatoshi Hashimoto, Yasushi Ito, Ryo Takahashi, Masaru Nakajima, Fumiyasu Matsubayashi, Satoko Saotome, Nozomi Kitamura, Tomoharu Sato, Takuyo Kozuka, Masahiko Oguchi
  • Organizer: ASTRO's 58th Annual Meeting
  • Place of Presentation: Boston Convention and Exhibition Center
  • Year and Date: 2016-09-25
  • Int'l Joint Research
• [Presentation] Four-dimensional Dose Reconstruction for Lung Cancer in VMAT (2016)
  • Author(s): Masatoshi Hashimoto, Yasushi Ito, Ryo Takahashi, Masaru Nakajima, Fumiyasu Matsubayashi, Satoko Saotome, Nozomi Kitamura, Tomoharu Sato, Takuyo Kozuka, Masahiko Oguchi
  • Organizer: ASTRO's 58th Annual Meeting
  • Place of Presentation: Boston Convention and Exhibition Center
  • Year and Date: 2016-09-25
  • Int'l Joint Research
• [Presentation] 距離画像センサを用いた患者セットアップシステム (2016)
  • Author(s): 橋本成世, 中野正寛, 伊藤康, 高橋良, 松林史康, 橋本竹雄, 芳賀昭弘, 名和要武, 佐藤智春, 小塚拓洋, 小口正彦
  • Organizer: 第112回日本医学物理学会学術大会
  • Place of Presentation: 沖縄コンベンションセンター
  • Year and Date: 2016-09-08
• [Presentation] 科研費取得による研究の発展 (2015)
  • Author(s): 橋本成世
  • Organizer: 第110回日本医学物理学術大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2015-09-19
  • Invited
• [Presentation] 肺がんに対するVMATにおける4次元線量再構成 (2015)
  • Author(s): 橋本成世、伊藤康、高橋良、高橋太郎、上間達也、五月女達子、明石華奈、松林史泰、作美明、坂田洞察、佐藤智春、小塚拓洋、小口正彦
  • Organizer: 第110回日本医学物理学術大会
  • Place of Presentation: 北海道大学
  • Year and Date: 2015-09-19
• [Patent(Industrial Property Rights)] 放射線治療支援システム, 画像生成法 (2016)
  • Inventor(s): 橋本成世
  • Industrial Property Rights Holder: 橋本成世
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2016-121730
  • Filing Date: 2016-06-20