Project/Area Number |
15K19234
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Epidemiology and preventive medicine
|
Research Institution | National Center for Child Health and Development |
Principal Investigator |
Maki Kawasaki 国立研究開発法人国立成育医療研究センター, 政策科学研究部, 非常勤医師 (00747488)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 妊娠糖尿病 / 授乳 / 2型糖尿病 / 膵臓β細胞保護 / 糖尿病発症予防 |
Outline of Final Research Achievements |
Recently, it has been reported from Western studies that lactation is associated with lower incidences of type 2 diabetes after gestational diabetes mellitus(GDM )pregnancy.In this study, we examined the effect of lactation on protection of pancreatic Bcell mass and preventing type 2 diabetes mellitus in women with GDM. We found no association between lactation intensity or lactation duration and incidences of type 2 diabetes.In exclusive lactation (no formula) group at 1 to 3 months after delivery ,HOMA-R at 3 months after birth and 1 year after birth was significantly lower and Disposition Index(DI) at 3 months after birth was significantly higher than that of incomplete lactation milk(formula,formula+lactation)group.
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