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Effectiveness of school closure on the epidemic of influenza in an island

Research Project

Project/Area Number 15K19245
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Hygiene and public health
Research InstitutionNagasaki University

Principal Investigator

SAITO Nobuo  長崎大学, 熱帯医学・グローバルヘルス研究科, 戦略職員 (60626018)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsインフルエンザ / ワクチン / 学校・学級閉鎖 / 罹患率
Outline of Final Research Achievements

This study analyzed the effectiveness of school exposure. However due to limited sample size of school closure in a Kamigoto island, the effectiveness was not able to be estimated. This study also analysed vaccine effectiveness because influenza vaccine is the most important strategy to prevent the epidemic. The vaccine effectiveness (VE) against influenza A and B were 32% and 13% ,respectively. This study was able to show the significant association between the low VE and previous exposure of influenza vaccine. This study showed the VE significantly decreased with dose dependent manner. This finding was firstly reported and published in the most influential international journal in infectious disease society,

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2018 2017 2015 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Dose-Dependent Negative Effects of Prior Multiple Vaccinations against Influenza A and Influenza B among School Children: A Study of Kamigoto Island in Japan during the 2011/12, 2012/13 and 2013/14 Influenza Seasons2018

    • Author(s)
      Saito Nobuo、Komori Kazuhiro、Suzuki Motoi、Kishikawa Takayuki、Yasaka Takahiro、Ariyoshi Koya
    • Journal Title

      Clinical Infectious Disease

      Volume: - Issue: 6 Pages: 897-904

    • DOI

      10.1093/cid/ciy202

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Negative impact of prior influenza vaccination on current influenza vaccination among people infected and not infected in prior season: A test-negative case-control study in Japan.2017

    • Author(s)
      Saito N, Komori K, Suzuki M, Morimoto K, Kishikawa T, Yasaka T, Ariyoshi K.
    • Journal Title

      Vaccine

      Volume: 35 Issue: 4 Pages: 687-693

    • DOI

      10.1016/j.vaccine.2016.11.024

    • NAID

      120006987577

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] インフルエンザワクチンの連続接種による減衰効果の検討2017

    • Author(s)
      齊藤信夫、小森一広 、岸川 孝、八坂貴宏 、鈴木基、森本浩之輔、有吉紅也
    • Organizer
      第91回日本感染症学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] インフルエンザBに対するワクチン連続接種の減衰効果についての検討2017

    • Author(s)
      齊藤信夫、小森一広 、岸川 孝、八坂貴宏 、鈴木基、森本浩之輔、有吉紅也
    • Organizer
      第1回臨床疫学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] インフルエンザワクチンの連続接種による減衰効果の検討2017

    • Author(s)
      齊藤信夫
    • Organizer
      感染症学会総会
    • Place of Presentation
      京王プラザホテル(東京、西新宿区)
    • Related Report
      2016 Research-status Report
  • [Presentation] インフルエンザ受診が翌シーズンのインフルエンザ受診に及ぼす効果2015

    • Author(s)
      齊藤 信夫
    • Organizer
      日本内科学会総会
    • Place of Presentation
      みやこめっせ(京都府・京都市)
    • Year and Date
      2015-04-10
    • Related Report
      2015 Research-status Report
  • [Remarks] 上五島インフルエンザ研究

    • URL

      http://www.tm.nagasaki-u.ac.jp/internal/lecturer.htm#60

    • Related Report
      2017 Annual Research Report

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Published: 2015-04-16   Modified: 2019-03-29  

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