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Establishment of new decompression therapy for chronic intestinal pseudo-obstruction

Research Project

Project/Area Number 15K19289
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field General internal medicine(including psychosomatic medicine)
Research InstitutionYokohama City University

Principal Investigator

OHKUBO Hidenori  横浜市立大学, 附属病院, 助教 (70622588)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords慢性偽性腸閉塞症 / 経胃瘻的空腸瘻減圧 / 経皮的減圧術 / 新規減圧治療の確立 / PEG-J / 新規減圧治療
Outline of Final Research Achievements

Chronic intestinal pseudo-obstruction (CIPO) is an intractable digestive disease which causes abdominal bloating, nausea, and malnutrition. Main treatment is a sustained decompression of dilated small bowel, however conventional method such as transnasal small intestinal tube placement is a heavy burden for patients because it causes terrible nasal pain and requires near-perpetual hospitalization.In this study,we assessed the efficacy and safety of percutaneous endoscopic gastro-jejunostomy (PEG-J) decompression therapy in CIPO patients. As a result,PEG-J decompression therapy can contribute greatly to improvement of abdominal symptoms and nutritional status in CIPO patients.PEG-J has the potential to be a noninvasive less painful novel decompression therapy for CIPO patients available at home.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (9 results)

All 2017 2016 2015

All Presentation (6 results) Book (3 results)

  • [Presentation] 本邦における慢性偽性腸閉塞症(CIPO)の 疫学、診断、治療の実態2017

    • Author(s)
      大久保秀則、冬木晶子、中島淳
    • Organizer
      第13回日本消化管学会総会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2017-02-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] 慢性偽性腸閉塞症(CIPO)の診断の進歩と新規治療法の提案2016

    • Author(s)
      大久保秀則、冬木晶子、中島淳
    • Organizer
      第71回日本大腸肛門学会学術集会
    • Place of Presentation
      三重県営サンアリーナ(三重県伊勢市)
    • Year and Date
      2016-11-18
    • Related Report
      2016 Annual Research Report
  • [Presentation] PEG-J の慢性偽性腸閉塞症(CIPO)に対する腸管減圧効果:有用性と安全性の検証2015

    • Author(s)
      大久保秀則、冬木晶子、中島淳
    • Organizer
      第17回日本神経消化器病学会
    • Place of Presentation
      沖縄科学技術大学院大学(沖縄県国頭郡恩納村)
    • Year and Date
      2015-11-11
    • Related Report
      2015 Research-status Report
  • [Presentation] PEG-Jを用いた慢性偽性腸閉塞症(CIPO)に対する腸管減圧の試み:A pilot study2015

    • Author(s)
      大久保秀則、冬木晶子、中島淳
    • Organizer
      第57回日本平滑筋学会総会
    • Place of Presentation
      山口大学医学部総合研究棟(山口県宇部市)
    • Year and Date
      2015-08-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 経皮内視鏡的胃空腸瘻造設術(PEG-J)による慢性偽性腸閉塞症(CIPO)に対する腸管減圧の試み2015

    • Author(s)
      大久保秀則、冬木晶子、中島淳
    • Organizer
      第89回日本消化器内視鏡学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-29
    • Related Report
      2015 Research-status Report
  • [Presentation] 慢偽性腸閉塞症患者における腹部症状と小腸蠕動異常の関連性2015

    • Author(s)
      冬木晶子、大久保秀則、中島淳
    • Organizer
      第101回日本消化器病学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2015-04-23
    • Related Report
      2015 Research-status Report
  • [Book] 消化器疾患最新の治療 2017-2018.2017

    • Author(s)
      大久保秀則、中島淳
    • Total Pages
      504
    • Publisher
      株式会社南江堂
    • Related Report
      2016 Annual Research Report
  • [Book] 消化器研修ノート 改訂第2版2016

    • Author(s)
      大久保秀則
    • Total Pages
      664
    • Publisher
      診断と治療社
    • Related Report
      2016 Annual Research Report
  • [Book] 慢性偽性腸閉塞 Chronic intestinal preudo-obstruction.2015

    • Author(s)
      大久保秀則,稲生優海,冬木晶子,飯田洋,中島淳
    • Total Pages
      7
    • Publisher
      日本臨牀
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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