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identification of M.avium complex and exacerbation factor of pulmonary MAC disease by mass spectrometry

Research Project

Project/Area Number 15K19416
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Respiratory organ internal medicine
Research InstitutionShinshu University

Principal Investigator

USHIKI Atsuhito  信州大学, 学術研究院医学系(医学部附属病院), 講師 (10467160)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords肺MAC症 / 肺非結核性抗酸菌症 / 質量分析
Outline of Final Research Achievements

Pulmonary MAC disease is an infectious disease of the lung by M. avium., and in recent years the number of patients has increased. Although the prognosis of this disease varies, it is not clear why the difference in prognosis. Mass spectrometry is a method for measuring the distribution of the molecular weight and identifying the sample. From the molecular weight distribution, it is also possible to analyze the protein contained in the sample. In this study, we examined identification of MAC and exacerbation factor of pulmonary MAC disease by mass spectrometry
We examined using 15 specimens, and it was possible to identify bacteria in 8 specimens. However, 7 specimens could not be identified due to fungal contamination or drying.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 2 results) Presentation (1 results)

  • [Journal Article] Health-related quality of life in patients with pulmonary non-tuberculous mycobacteria infection.2016

    • Author(s)
      Hama M, Ushiki A, Kosaka M, Yamazaki Y, Yasuo M, Yamamoto H, Hanaoka M
    • Journal Title

      Int J Tuberc Lung Dis

      Volume: 20 Issue: 6 Pages: 747-752

    • DOI

      10.5588/ijtld.15.0460

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A case of pulmonary Mycobacterium avium infection in an immunocompetent patient who showed a huge consolidation with a high FDG uptake on PET/CT.2016

    • Author(s)
      Kato A, Yamamoto H, Ikeda M, Tateishi K, Ushiki A, Yasuo M, Kawakami S, Asaka S, Oguchi K, Hanaoka M
    • Journal Title

      Respir Med Case Rep

      Volume: 19 Pages: 49-52

    • DOI

      10.1016/j.rmcr.2016.07.004

    • NAID

      120007100157

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] CAM、RFP、EB治療で改善したMycobacterium shinjukuense肺感染症の1例2016

    • Author(s)
      山中美和、西江健一、北口良晃、小林信光、立石一成、牛木淳人、安尾将法、漆畑一寿、山本 洋、花岡正幸
    • Organizer
      第170回日本結核病学会関東支部会 第221回日本呼吸器学会関東地方会合同学会
    • Place of Presentation
      名古屋市
    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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