Impact of a specific gut microbiota change on acute kidney injury mice
Project/Area Number |
15K19450
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Kidney internal medicine
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Research Institution | Kanazawa University |
Principal Investigator |
Nakade Yusuke 金沢大学, 附属病院, 臨床検査技師 (10749360)
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Project Period (FY) |
2015-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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Keywords | 腸内細菌 / 腎臓病 / バイオマーカー / 腸内細菌叢 / 臓器連関 / 腎臓 / 新規バイオマーカー / 治療 |
Outline of Final Research Achievements |
The aim of this study was to reveal the relationship between gut microbiota and kidney disease and to identify new biomarkers for kidney diseases. The contribution of gut microbiota to various disorders has been reported in recent years. However, the association of gut microbiota with kidney disease remains to be investigated. We revealed the alteration of gut bacteria in acute kidney injury mice with 16S rRNA analysis. This result raise the possibility that gut bacteria could be a new candidate of biomarkers for acute kidney injury. A patent has been applied for the biomarker of kidney injury according to our results.
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Report
(3 results)
Research Products
(9 results)
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[Journal Article] Impact of kidney function and urinary protein excretion on intima-media thickness in Japanese patients with type 2 diabetes.2015
Author(s)
Nakade Y, Toyama T, Furuichi K, Kitajima S, Miyajima Y, Fukamachi M, Sagara A, Shinozaki Y, Hara A, Shimizu M, Iwata Y, Oe H, Nagahara M, Horita H, Sakai Y, Kaneko S, Wada T.
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Journal Title
Clin Exp Nephrol.
Volume: 19
Issue: 5
Pages: 909-917
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Impact of kidney function and urinary protein excretion on pulmonary function2015
Author(s)
Yusuke Nakade, Tadashi Toyama, Kengo Furuichi, Shinji Kitajima, Yasuyuki Shinozaki, Akinori Hara, Miho Shimizu, Yasunori Iwata, Norihiko Sakai, Takashi Wada
Organizer
KIDNEY WEEK 2015
Place of Presentation
San Diego, CA, USA
Year and Date
2015-11-04
Related Report
Int'l Joint Research
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[Presentation] Impact of kidney function on intima-media thickness in patients with type 2 diabetes2015
Author(s)
Yusuke Nakade, Tadashi Toyama, Kengo Furuichi, Shinji Kitajima, Akihiro Sagara, Yasuyuki Shinozaki, Akinori Hara, Miho Shimizu, Yasunori Iwata, Norihiko Sakai, Takashi Wada
Organizer
KIDNEY WEEK 2015
Place of Presentation
San Diego, CA, USA
Year and Date
2015-11-04
Related Report
Int'l Joint Research
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