| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
It is unclear how the underlying chronic inflammation in lifestyle-related diseases affects on the process of transition from AKI to CKD. In the chronic phase after IRI to the unilateral kidney of B6 mouse, the injured side kidney becomes atrophic. Although similar experiments were conducted using DIO and db/db mice as MetS models, a large amount of subcutaneous fats made it difficult to stabilize the IRI technical procedure enough to evaluate the chronic renal injury. Now, the pathway gene analysis by PCR array is in progress using chronic AKI tissues.
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