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Impact of diabetes mellitus on peripheral artery disease

Research Project

Project/Area Number 15K19515
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Metabolomics
Research InstitutionOsaka University

Principal Investigator

TAKAHARA Mitsuyoshi  大阪大学, 医学系研究科, 寄附講座助教 (00751067)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords末梢動脈疾患 / 糖尿病
Outline of Final Research Achievements

The impact of diabetes on prognosis in patients with peripheral artery disease and the risk of peripheral artery disease in diabetic patients were investigated. In patients with peripheral artery disease, diabetes was associated with major amputation. In cases with critical limb ischemia, diabetes was associated with blow-the-knee lesion and arterial calcification, as well as an increased risk of major adverse limb events after endovascular therapy. Diabetes had a potential to influence the association of revascularization strategies and clinical outcomes. In diabetic patients, peripheral neuropathy was not directly correlated with peripheral artery disease. The assessment of borderline anke-brachial index was associated with improved diagnostic accuracy of peripheral artery disease.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2018 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Journal Article] Critical Limb Ischemia in Japan: Clinical Impact of Diabetes Mellitus, Dialysis, and Subclinical Critical Limb Ischemia2017

    • Author(s)
      高原充佳
    • Journal Title

      The Journal of Japanese College of Angiology

      Volume: 57 Issue: 10 Pages: 139-144

    • DOI

      10.7133/jca.17-00015

    • NAID

      130006163788

    • ISSN
      0387-1126, 1880-8840
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 末梢動脈疾患リスク予測における境界域ABIの意義の検討2018

    • Author(s)
      高原充佳、藤原優子、片上直人、坂本扶美枝、松岡孝昭、下村伊一郎
    • Organizer
      第61回糖尿病学会年次学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 糖尿病患者における血行障害のエビデンス2018

    • Author(s)
      高原充佳
    • Organizer
      第10回日本下肢救済・足病学会学術集会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Diabetes and risk management of critical limb ischemia2017

    • Author(s)
      Mitsuyoshi Takahara
    • Organizer
      3rd Korea-Japan Diabetes Forum
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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