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Regulation of inflammation by SOCS1 and SOCS3 in the syngeneic bone marrow transplantation

Research Project

Project/Area Number 15K19547
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Hematology
Research InstitutionNiigata University

Principal Investigator

Ushiki Takashi  新潟大学, 医歯学総合病院, 講師 (80579152)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsSOCS1 / SOCS3 / 慢性炎症 / 遺伝子間相互作用 / 骨髄移植 / SOCS / GVHD
Outline of Final Research Achievements

Combined hematopoietic loss of SOCS1 and SOCS3 causes rapid inflammatory disease in the syngeneic bone marrow transplantation. Loss of SOCS1 increases the number of CD8+CD44high cells. The expression of homing markers on these T cells may facilitate migration to organs and tissues, and the propensity for production of pro-inflammatory cytokines and chemokines, such as RANTES, MIP1a, GM-CSF and IL-3 for recruiting myeloid cells, as well as development of high circulating G-CSF concentrations, can account for the pathological infiltration of neutrophils, monocytes, eosinophils and lymphocytes at the numerous sites of inflammation in SOCS1KO mice. Our data extend the model to suggest that the absence of SOCS3 in the already pro-inflammatory environment established by SOCS1 deficiency, results in hyper-responsiveness of immune cells to cytokines such as G-CSF and IL-6, and dramatically accelerates myeloid proliferation and inflammatory infiltration of target tissues.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (63 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (3 results) Journal Article (12 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 12 results,  Open Access: 3 results) Presentation (48 results) (of which Int'l Joint Research: 10 results,  Invited: 1 results)

  • [Int'l Joint Research] ウォルター・エライザ・ホール医学研究所(オーストラリア)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] ウォルター・エライザ・ホール医学研究所(オーストラリア)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] ウォルター・エライザ・ホール医学研究所(オーストラリア)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Myelodysplastic syndrome with refractory hemorrhage due to reduced platelet aggregation activity2017

    • Author(s)
      Tanaka T, Kozakai T, Kitajima T, Fuse K, Kobayashi H, Ushiki T, Shibazaki Y, Moriyama M, Takizawa J, Sone H, Fuse I, Masuko M
    • Journal Title

      Rinsho Ketsueki

      Volume: 58 Issue: 12 Pages: 2402-2405

    • DOI

      10.11406/rinketsu.58.2402

    • NAID

      130006308822

    • ISSN
      0485-1439, 1882-0824
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Successful 5-azacytidine treatment of myeloid sarcoma and leukemia cutis associated with myelodysplastic syndrome2017

    • Author(s)
      Katagiri Takayuki、Ushiki Takashi、Masuko Masayoshi、Tanaka Tomoyuki、Miyakoshi Shukuko、Fuse Kyoko、Shibasaki Yasuhiko、Takizawa Jun、Aoki Sadao、Sone Hirohito
    • Journal Title

      Medicine

      Volume: 96 Issue: 36 Pages: e7975-e7975

    • DOI

      10.1097/md.0000000000007975

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Peripheral T-cell lymphoma, not otherwise specified: a retrospective single-center analysis2017

    • Author(s)
      鈴木 隆晴、柴崎 康彦、森山 雅人、増子 正義、成田 美和子、曽根 博仁、青木 定夫、中村 直哉、大島 孝一、瀧澤 淳、河本 啓介、田村 秀、上村 駿、海發 茜、根本 洋樹、小林 弘典、牛木 隆志、布施 香子
    • Journal Title

      Rinsho Ketsueki

      Volume: 58 Issue: 8 Pages: 905-911

    • DOI

      10.11406/rinketsu.58.905

    • NAID

      130006067957

    • ISSN
      0485-1439, 1882-0824
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Glasgow Prognostic Score as a pre-transplant risk assessment for allogeneic hematopoietic cell transplantation2017

    • Author(s)
      Shibasaki Yasuhiko、Suwabe Tatsuya、Katagiri Takayuki、Tanaka Tomoyuki、Kobayashi Hironori、Fuse Kyoko、Ushiki Takashi、Sato Naoko、Yano Toshio、Kuroha Takashi、Hashimoto Shigeo、Narita Miwako、Furukawa Tatsuo、Sone Hirohito、Masuko Masayoshi
    • Journal Title

      Clinical Transplantation

      Volume: 31 Issue: 11

    • DOI

      10.1111/ctr.13103

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Successful umbilical cord blood hematopoietic stem cell transplantation in a patient with adult T-cell leukemia/lymphoma initially achieving complete remission with anti-CC chemokine receptor 4 antibody combined chemotherapy2017

    • Author(s)
      Suwabe T, Shibasaki Y, Kaihatsu A, Katagiri T, Miyakoshi S, Fuse K, Kobayashi H, Ushiki T, Moriyama M, Takizawa J, Narita M, Sone H, Masuko M.
    • Journal Title

      Rinsho Ketsueki

      Volume: 58 Issue: 1 Pages: 32-36

    • DOI

      10.11406/rinketsu.58.32

    • NAID

      130005394599

    • ISSN
      0485-1439, 1882-0824
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells2016

    • Author(s)
      Ushiki T, Huntington ND, Glaser SP, Kiu H, Georgiou A, Zhang JG, Metcalf D, Nicola NA, Roberts AW, Alexander WS
    • Journal Title

      PLoS One

      Volume: Sep 1;11(9) Issue: 9 Pages: e0162111-e0162111

    • DOI

      10.1371/journal.pone.0162111

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] CIS is a potent checkpoint in NK cell-mediated tumor immunity2016

    • Author(s)
      Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, et al.
    • Journal Title

      Nature Immunology

      Volume: Jul;17(7) Issue: 7 Pages: 816-824

    • DOI

      10.1038/ni.3470

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The Dinakara equation for adjusting DLCO for hemoglobin in the HCT-CI is superior to the Cotes equation for predicting high-risk patients in allogeneic hematopoietic stem cell transplantation.2016

    • Author(s)
      Shibasaki Y, Katagiri T, Kobayashi H, Ushiki T, Narita M, Sone H, Furukawa T, Masuko M
    • Journal Title

      Am J Hematol.

      Volume: Volume 91, Issue 5 Issue: 5

    • DOI

      10.1002/ajh.24318

    • Related Report
      2016 Research-status Report 2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] CIS is a potent checkpoint in NK cell-mediated tumour immunity.2016

    • Author(s)
      Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM,, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, et al.
    • Journal Title

      Nature Immunology

      Volume: in press

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.2016

    • Author(s)
      Delconte RB, Shi W, Sathe P, Ushiki T, Seillet C, Minnich M, Kolesnik TB, Rankin LC, Mielke LA, Zhang JG, Busslinger M, Smyth MJ, Hutchinson DS, Nutt SL, Nicholson SE, Alexander WS, Corcoran LM, Vivier E, Belz GT, Carotta S, Huntington ND
    • Journal Title

      Immunity

      Volume: Volume 44, Issue 1 Issue: 1 Pages: 103-115

    • DOI

      10.1016/j.immuni.2015.12.007

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Possible Involvement of Lung Cells Harboring an Abnormal Karyotype in the Pathogenesis of Pulmonary Alveolar Proteinosis Associated with Myelodysplastic Syndrome.2015

    • Author(s)
      Moriyama M, Yano T, Furukawa T, Takada T, Ushiki T, Masuko M, Takizawa J, Sone H, Tazawa R, Saijo Y, Ishii H, Nakata K
    • Journal Title

      Ann Am Thorac Soc.

      Volume: Vol. 12, No. 8 Pages: 1251-1253

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] The association of level of reduction of Wilms' tumor gene 1 mRNA transcript in bone marrow and outcome in acute myeloid leukemia patients.2015

    • Author(s)
      Shibasaki Y, Seki Y, Tanaka T, Miyakoshi S, Fuse K, Kozakai T, Kobayashi H, Ushiki T, Abe T, Yano T, Moriyama M, Kuroha T, Isahai N, Takizawa J, Narita M, Koyama S, Furukawa T, Sone H, Masuko M
    • Journal Title

      Leuk Res.

      Volume: Volume 39, Issue 6 Issue: 6 Pages: 667-671

    • DOI

      10.1016/j.leukres.2015.03.021

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] 骨膜シートは移植局所に骨髄由来造血細胞を動員する2018

    • Author(s)
      上松晃也、石黒 創、牛木隆志、永田昌毅、星名秀行、今井秀明、中田 光、川瀬知之
    • Organizer
      第17回日本再生医療学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ヒト下顎骨分散骨膜細胞のゼノフリー骨分化誘導試験2018

    • Author(s)
      伊藤祐子、米山奈保、牛木隆志、川瀬知之、中田 光、對比地久義、伊藤 彰、中村孝人
    • Organizer
      第17回日本再生医療学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Tissue-engineered human osteogenic periosteal sheets recruit bone marrow stem cells to their implantation sites2018

    • Author(s)
      Uematsu K, Ishiguro H, Ushiki T, Nagata M, Nakata K, Kawase T
    • Organizer
      Academy of Osseointegration 2018 Annual meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マーカー染色体が急性骨髄性白血病に対する同種造血細胞移植成績に与える影響2018

    • Author(s)
      田中智之、布施香子、諏訪部達也、笠見卓哉、河本啓介、牛木隆志、森山雅人、柴崎康彦、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第40回日本造血細胞移植学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 機械学習を用いた急性白血病における造血幹細胞移植後の患者ベースの再発予測モデルと個別化治療への応用2018

    • Author(s)
      布施香子、上村駿、諏訪部達也、片桐隆幸、笠見卓哉、田中智之、難波亜矢子、牛木隆志、柴崎康彦、佐藤直子、矢野敏雄、黒羽高志、橋本誠雄、古川達雄、成田美和子、曽根博仁、増子正義
    • Organizer
      第40回日本造血細胞移植学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ヒトPlatelet-rich fibrin抽出物を用いた異種血清を用いない間葉系幹細胞培養系の開発2017

    • Author(s)
      伊藤祐子、米山奈保、牛木隆志、川瀬知之、中田 光、對比地久義、伊藤 彰、中村孝人
    • Organizer
      第16回日本再生医療学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-07
    • Related Report
      2016 Research-status Report
  • [Presentation] 臍帯血移植後に広範なHLA抗体の産生をきたし生着不全に至った血管免疫芽球性リンパ腫の一例2017

    • Author(s)
      田村秀、上村駿、海發茜、鈴木隆晴、根本洋樹、小林弘典、牛木隆志、布施香子、柴崎康彦、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第39回日本造血細胞移植学会総会
    • Place of Presentation
      くにびきメッセ・島根県民会館(島根県松江市)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Research-status Report
  • [Presentation] 同種造血幹細胞移植において生着後早期の免疫再構築はドナーソースや移植法により異なる2017

    • Author(s)
      上村駿、柴崎康彦、片桐隆幸、井藤ヒロミ、海發茜、田村秀、鈴木隆晴、根本洋樹、小林弘典、布施香子、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第39回日本造血細胞移植学会総会
    • Place of Presentation
      くにびきメッセ・島根県民会館(島根県松江市)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Research-status Report
  • [Presentation] 樹木構造接近法を用いた急性白血病、骨髄異形成症候群に対する造血細胞移植後の予後因子の解析2017

    • Author(s)
      布施香子、上村駿、海發茜、鈴木隆晴、田村秀、片桐隆幸、根本洋樹、小林弘典、牛木隆志、柴崎康彦、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第39回日本造血細胞移植学会総会
    • Place of Presentation
      くにびきメッセ・島根県民会館(島根県松江市)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Research-status Report
  • [Presentation] 移植後長期フォローアップにおける再発の早期発見を目的とした末梢血STR法の有用性2017

    • Author(s)
      海發茜、柴崎康彦、中村岳史、椎谷恵子、和田玲子、田村秀、鈴木隆晴、上村駿、片桐隆幸、根本洋樹、小林弘典、布施香子、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第39回日本造血細胞移植学会総会
    • Place of Presentation
      くにびきメッセ・島根県民会館(島根県松江市)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Research-status Report
  • [Presentation] Patient-Based Prediction Algorithm of Relapse after Allo-HSCT for Acute Leukemia Using Machine Learning Approach2017

    • Author(s)
      Fuse K, Uemura S, Suwabe T, Katagiri T, Tanaka T, Ushiki T, Shibasaki Y, Sato N, Yano T, Kuroha T, Hashimoto S, Furukawa T, Narita M, Sone H, Masuko M
    • Organizer
      59th American Society of Hematology Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Further Prognostic Factors for Stratification of Patients in the High-Risk HCT-CI Group Undergoing Allogeneic HCT2017

    • Author(s)
      Shibasaki Y, Suwabe T, Uemura S, Katagiri T, Tanaka T, Ushiki T, Fuse K, Narita M, Sone H, Masuko M
    • Organizer
      59th American Society of Hematology Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] TKI時代においてフィラデルフィア染色体陽性は移植後の予後不良因子ではない2017

    • Author(s)
      上村駿、布施香子、片桐隆幸、田中智之、小林弘典、牛木隆志、柴崎康彦、成田美和子、曽根博仁、増子正義
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 移植前予後予測モデルとしての同種造血細胞移植特異的Glasgow Prognostic Score2017

    • Author(s)
      柴崎康彦、諏訪部達也、片桐隆幸、田中智之、小林弘典、布施香子、牛木隆志、成田美和子、曽根博仁、増子正義
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 臍帯血移植後著明な肝萎縮と治療抵抗性腹水を合併したAITLの一例2017

    • Author(s)
      小堺貴司、柴崎康彦、田村秀、牛木隆志、布施香子、瀧澤 淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第79回日本血液学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 新潟大学医歯学総合病院における細胞治療管理体制と輸血部技師が細胞治療運用に及ぼす役割2017

    • Author(s)
      牛木隆志
    • Organizer
      第144回日本輸血・細胞治療学会 関東甲信越支部例会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 当院における細胞製品一元管理体制構築の試み2017

    • Author(s)
      青木寿成、上村正巳、藤本陽子、渡辺真理、佐藤美里、大木直江、増子正義、牛木隆志
    • Organizer
      第65回日本輸血・細胞治療学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 不規則抗体スクリーニングにおけるCapture法の抗体検出能の検討2017

    • Author(s)
      渡部もも、上村正巳、青木寿成、佐藤美里、大木直江、増子正義、中田 光、牛木隆志
    • Organizer
      第65回日本輸血・細胞治療学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Unique profile of immune reconstruction after three types of HLA-mismatched allogeneic hematopoietic cell transplantations2017

    • Author(s)
      Uemura S, Shibasaki Y, Katagiri T, Ito H, Tanaka T, Kobayashi H, Ushiki T, Fuse K, Narita M, Sone H, Masuko M
    • Organizer
      The 8th JSH International Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 臍帯血移植後にヒトパルボウイルスB19感染による自己免疫性貧血と赤芽球癆を発症した1例2017

    • Author(s)
      海發茜、柴崎康彦、上村駿、田村秀、小堺貴司、難波亜矢子、小林弘典、布施香子、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第6回日本血液学会関東甲信越地方会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Elucidation of Tumor-Promoting Effects of Novel Adherent Immature Myeloid Cells in Tumor2016

    • Author(s)
      Tsubaki T, Kadonosono T, Shiozawa T, Kuchimaru T, Ushiki T, Masuko M, Kizaka-Kondoh S
    • Organizer
      58th American Society of Hematology Annual Meeting (ASH)
    • Place of Presentation
      San Diego Convention Center (San Diego, CA, USA)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Evaluation of Liver Iron Deposition in Transfusion-Dependent Patients By Dual-Energy CT2016

    • Author(s)
      Kobayashi H, Yoshimura N, Katagiri T, Ushiki T, Fuse K, Shibasaki Y, Narita M, Sone H, Masuko M
    • Organizer
      58th American Society of Hematology Annual Meeting (ASH)
    • Place of Presentation
      San Diego Convention Center (San Diego, CA, USA)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The Predictive Factors of Favorable Prognosis after Allo-HSCT for Refractory Acute Leukemia2016

    • Author(s)
      Fuse K, Katagiri T, Shibasaki Y, Tanaka T, Ushiki T, Sato N, Yano T, Kuroha T, Hashimoto S, Furukawa T, Narita M, Sone H, Masuko M
    • Organizer
      58th American Society of Hematology Annual Meeting (ASH)
    • Place of Presentation
      San Diego Convention Center (San Diego, CA, USA)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Successful AML-type therapy switched from pre-phase PSL for mixed phenotype acute leukemia T/M, NOS2016

    • Author(s)
      上村駿、布施香子、柴崎康彦、根本洋樹、小林弘典、牛木隆志、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第78回日本血液学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-13
    • Related Report
      2016 Research-status Report
  • [Presentation] Retrospective analysis of AITL in Niigata University Medical and Dental Hospital2016

    • Author(s)
      田村秀、鈴木隆晴、上村駿、海發茜、根本洋樹、笠見卓哉、河本啓介、小林弘典、牛木隆志、布施香子、柴崎康彦、森山雅人、増子正義、成田美和子、曽根博仁、瀧澤淳、中村直哉、大島孝一
    • Organizer
      第78回日本血液学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-13
    • Related Report
      2016 Research-status Report
  • [Presentation] SOCS1 and SOCS3 work coordinately in inflammation by affecting cell differentiation2016

    • Author(s)
      Ushiki T, Roberts A, Alexander W
    • Organizer
      第78回日本血液学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-13
    • Related Report
      2016 Research-status Report
  • [Presentation] The predictive factors of favorable prognosis after allo-HSCT to refractory acute leukemia2016

    • Author(s)
      布施香子、 柴崎康彦、片桐隆幸、小林弘典、牛木隆志、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第78回日本血液学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-13
    • Related Report
      2016 Research-status Report
  • [Presentation] A pre-transplant biomarker risk index based on serum ferritin, albumin, and C-reactive protein levels that can predict the outcomes of allogeneic hematopoietic stem cell transplantation independently of the HCT-CI2016

    • Author(s)
      Suwabe T, Shibasaki Y, Katagiri T, Miyakoshi S, Kobayashi H, Fuse K, Ushiki T, Sato N, Yano T, Moriyama M, Kuroha T, Takizawa J, Hashimoto S, Narita M, Furukawa T, Sone H, Masuko M
    • Organizer
      21st Congress of European Hematology Association (EHA)
    • Place of Presentation
      The Bella Center (Copenhagen, Denmark)
    • Year and Date
      2016-06-09
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 当科におけるIVLBCL 14例の臨床病理学的検討2016

    • Author(s)
      諏訪部達也、河本啓介、片桐隆幸、宮腰淑子、小林弘典、牛木隆志、布施香子、柴崎康彦、森山雅人、増子正義、成田美和子、曽根博仁、瀧澤淳、中村直哉、大島孝一
    • Organizer
      第56回日本リンパ網内系学会総会
    • Place of Presentation
      ホテル日航熊本(熊本県熊本市)
    • Year and Date
      2016-05-19
    • Related Report
      2016 Research-status Report
  • [Presentation] 当院において交差適合試験を3日間に短縮するための課題2016

    • Author(s)
      上村正巳, 青木寿成, 佐藤美里, 大木直江, 増子正義, 牛木隆志
    • Organizer
      第64回日本輸血・細胞治療学会総会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-28
    • Related Report
      2016 Research-status Report
  • [Presentation] 再生医療新法における当院輸血部の対応~臨床検査技師の経験から~2016

    • Author(s)
      青木寿成, 上村正巳, 佐藤美里, 大木直江, 増子正義, 牛木隆志
    • Organizer
      第64回日本輸血・細胞治療学会総会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-28
    • Related Report
      2016 Research-status Report
  • [Presentation] 抗CCR4抗体併用化学療法により寛解が得られた後に臍帯血移植を行ったATLLの1例2016

    • Author(s)
      諏訪部 達也、柴崎康彦、片桐隆幸、宮腰淑子、布施香子、小林弘典、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第4回日本血液学会関東甲信越地方会
    • Place of Presentation
      ホテル東京ガーデンパレス (東京都文京区)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
  • [Presentation] ヒトPlatelet-rich fibrin抽出物はウシ胎児血清(FBS)の代替となり得るか?2016

    • Author(s)
      伊藤祐子、川瀬知之、牛木隆志、中田光、對比地久義、伊藤彰、中村孝人
    • Organizer
      第15回日本再生医療学会総会
    • Place of Presentation
      大阪国際会議場 (大阪府大阪市)
    • Year and Date
      2016-03-17
    • Related Report
      2015 Research-status Report
  • [Presentation] アルブミン、フェリチン、CRP を用いた Biomarker indexは、造血幹細胞移植前患者に対する HCT-CI とは独立した予後予測因子である2016

    • Author(s)
      諏訪部達也、柴崎康彦、宮腰淑子、布施香子、小林弘典、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第38回日本造血細胞移植学会総会
    • Place of Presentation
      名古屋国際会議場 (愛知県名古屋市)
    • Year and Date
      2016-03-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 当科におけるPTCL、NOS28例の臨床病理学的解析2016

    • Author(s)
      鈴木隆晴、田村秀、上村駿、海發茜、河本啓介、根本洋樹、小林弘典、牛木隆志、布施香子、柴崎康彦、森山雅人、増子正義、成田美和子、曽根博仁、青木定夫、中村直哉、大島孝一、瀧澤淳
    • Organizer
      第5回日本血液学会関東甲信越地方会
    • Place of Presentation
      新潟日報メディアシップ(新潟県新潟市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 扁桃・リンパ節に多発性myeloid sarcomaを生じたMDSの1例2016

    • Author(s)
      片桐隆幸、牛木隆志、田中智之、宮越淑子、難波亜矢子、河本啓介、柴崎康彦、瀧澤淳、成田美和子、曽根博仁、青木定夫、増子正義
    • Organizer
      第5回日本血液学会関東甲信越地方会
    • Place of Presentation
      新潟日報メディアシップ(新潟県新潟市)
    • Related Report
      2016 Research-status Report
  • [Presentation] The clinical relevance of HCT-CI/age score as pre-transplant assessment for recipients2015

    • Author(s)
      片桐隆幸、柴崎康彦、諏訪部達也、宮腰淑子、布施香子、小林弘典、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、増子正義
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      ANAクラウンプラザホテル金沢 (石川県金沢市)
    • Year and Date
      2015-10-16
    • Related Report
      2015 Research-status Report
  • [Presentation] Both low γ/δ T cells and high Treg cells after HSCT is an independent risk factor for relapse2015

    • Author(s)
      柴崎康彦、宮腰淑子、諏訪部達也、片桐隆幸、布施香子、小林弘典、牛木隆志、森山雅人、瀧澤淳、成田美和子、曽根博仁、古川達雄、増子正義
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      ANAクラウンプラザホテル金沢 (石川県金沢市)
    • Year and Date
      2015-10-16
    • Related Report
      2015 Research-status Report
  • [Presentation] 再発時CCND1転座陽性となったCD5陽性MALTリンパ腫の1例2015

    • Author(s)
      根本洋樹、笠見卓哉、片桐隆幸、河本啓介、小林弘典、牛木隆志、柴崎康彦、森山雅人、増子正義、成田美和子、曽根博仁、瀧澤淳、大湊絢、張大行、尾山徳秀、福地健郎、竹内賢吾、中村直哉、栗田大輔、市川理子、大島孝一
    • Organizer
      第55回日本リンパ網内系学会総会
    • Place of Presentation
      岡山コンベンションセンター (岡山県岡山市)
    • Year and Date
      2015-07-09
    • Related Report
      2015 Research-status Report
  • [Presentation] MYC転座とBCL2転座を認めたCD20陰性EBV陽性胃原発B細胞リンパ腫の一例2015

    • Author(s)
      笠見卓哉、根本洋樹、片桐隆幸、河本啓介、小林弘典、牛木隆志、柴崎康彦、森山雅人、増子正義、成田美和子、曽根博仁、瀧澤淳、橋口俊洋、栗田大輔、大島孝一
    • Organizer
      第55回日本リンパ網内系学会総会
    • Place of Presentation
      岡山コンベンションセンター (岡山県岡山市)
    • Year and Date
      2015-07-09
    • Related Report
      2015 Research-status Report
  • [Presentation] 脳死両肺移植後の小腸DLBCL発症に対して化学療法施行後に気管支アスペルギローシスを発症した1例2015

    • Author(s)
      河本啓介,佐藤征二郎,根本洋樹,小林弘典,柴崎康彦,牛木隆志,森山雅人,瀧澤淳,成田美和子,土田正則,曽根博仁,増子正義
    • Organizer
      第3回日本血液学会関東甲信越地方会
    • Place of Presentation
      つくば国際会議場 (茨城県つくば市)
    • Year and Date
      2015-07-04
    • Related Report
      2015 Research-status Report
  • [Presentation] PERIPHERAL BLOOD EOSINOPHIL COUNT AT DAY 28 AS A PROGNOSTIC INDICATOR IN ALLOGENEIC.2015

    • Author(s)
      Kawamoto K, Shibasaki Y, Kobayashi H, Ushiki T, Sato N, Yano T, Moriyama M, Kuroha T, Takizawa J, Hashimoto S, Narita M, Furukawa T, Sone H, Masuko M
    • Organizer
      20th Congress of European Hematology Association (EHA)
    • Place of Presentation
      Messe Wien Exhibition & Congress Center (Vienna, Austria)
    • Year and Date
      2015-06-11
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 不規則抗体スクリーニング検査より酵素法を省略したことによる影響の検証2015

    • Author(s)
      上村正巳、青木寿成、佐藤美里、大木直江、中田光、牛木隆志
    • Organizer
      第63回日本輸血・細胞治療学会総会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2015-05-28
    • Related Report
      2015 Research-status Report
  • [Presentation] 新潟大学医歯学総合病院でのABO血液型抗原減弱例の調査報告2015

    • Author(s)
      青木寿成、上村正巳、佐藤美里、大木直江、増子正義、中田光、牛木隆志
    • Organizer
      第63回日本輸血・細胞治療学会総会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2015-05-28
    • Related Report
      2015 Research-status Report
  • [Presentation] 大学病院における他職種連携によるアルブミン査定減少の取り組み2015

    • Author(s)
      佐藤美里、堀田哲夫、若井俊文、田澤由紀子、青山孝明、青木寿成、名村理、古谷健太、小林晴男、増子正義、中田光、牛木隆志
    • Organizer
      第63回 日本輸血・細胞治療学会総会
    • Place of Presentation
      京王プラザホテル (東京都新宿区)
    • Year and Date
      2015-05-28
    • Related Report
      2015 Research-status Report
  • [Presentation] The clinical relevance of MDS Transplantation Risk Index in allogeneic hematopoietic stem cell transplantation for patents.2015

    • Author(s)
      Katagiri T, Shibasaki Y, Kobayashi H, Ushiki T, Sato N, Yano T, Moriyama M, Kuroha T, Takizawa J, Hashimoto M, Narita M, Sone H, Furukawa T, Masuko M
    • Organizer
      The 6th JSH International Symposium 2015
    • Place of Presentation
      Karuizawa Prince Hotel West (Karuizawa, Japan)
    • Year and Date
      2015-05-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 同種造血幹細胞移植成績における血清蛋白と発熱・炎症反応との関連性の検討2015

    • Author(s)
      森山雅人、柴崎康彦、増子正義、根本洋樹、片桐隆幸、笠見卓哉、河本啓介、田中智之、宮越淑子、小堺貴司、小林弘典、布施香子、牛木隆志、瀧澤淳、成田美和子、高橋益廣、曽根博仁、西條康夫
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府市総合市民会館 (山梨県甲府市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Research-status Report
  • [Presentation] 妊娠を契機に診断されたUpshaw-Schulman症候群症例における第二子妊娠の周産期管理2015

    • Author(s)
      森山雅人、玉木悦子、松本雅則、石西綾美、松本吉史、冨永麻理恵、工藤理沙、安達聡介、生野寿史、高桑好一、宮越淑子、小堺貴司、小林弘典、牛木隆志、柴崎康彦、増子正義、瀧澤淳、成田美和子、曽根博仁、西條康夫
    • Organizer
      第37回日本血栓止血学会学術集会
    • Place of Presentation
      甲府市総合市民会館 (山梨県甲府市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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