| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
The purpose of this study is to show whether the gut barrier maturation of infants is affected by microbiota of mother. The expression level of several tight junction proteins, which regulate intestinal barrier function, was increased depending on the week-old. Next, I analyzed whether the gut barrier maturation of infants is changed or not, after changing the microbiota of mother by administration of pro-biotics and polyphenol. It is suggested that a particular lactobacillus and resveratrol affect to the gut barrier function.
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