The pathogenesisiof Henoch-schoenlein purpura nephritis: Role of circulation of defective forms of IgA1.
| Project/Area Number |
15K19624
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pediatrics
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 紫斑病性腎炎 / 小児 / 慢性腎障害 |
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| Outline of Final Research Achievements |
It has been reported that the pathogenesis of Henoch-Shoenlein purpura nephritis (HSPN）may be associated with the circulation of defective forms of IgA1 or the presence of in situ immune complexes, and the onset and progression of inflammation are thought to be associated with complement components, activated macrophage and mesangial cells. It is important to control HSPN activity including steroid and immunosuppressive drugs.
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Report
(3 results)
Research Products
(18 results)
