• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

he establishment of the new intestinal growth rating system in the premature infant and bowel protection strategy

Research Project

Project/Area Number 15K19649
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Embryonic/Neonatal medicine
Research InstitutionUniversity of Fukui

Principal Investigator

Okuno Takashi  福井大学, 学術研究院医学系部門(附属病院部), 助教 (80634188)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords未熟児腸管発育 / サイトカイン / 新生児乳児消化管アレルギー / 未熟児 / 腸管発育 / 消化管発育 / 新生児 / 腸保護 / 経腸栄養
Outline of Final Research Achievements

We analyzed the clinical course such as a digestion, nutritional status of the milk of the very low birth weight infant, abdominal findings, and measured blood, urine cytokine which was thought to have intestinal growth promotion effects with clinical specimen. Using Bio-Plex cytokine assay, we measured 27 kinds of cytokine with serum and urine within one month after the life. We showed increase of serum IL-6, IL-8, IL-10, IL-12, IL-17, VEGF in a dyspeptic group. Inflammatory cytokine is associated with the gastrointestinal growth of the premature infant and we consider that the administration of drug with an anti-inflammatory response may be effective.
In the process of the study, we reported one rare case that immediate-type allergy was associated, extremely-low-birth-weight infants of the neonatal infantile gastrointestinal allergy.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2017

All Presentation (1 results)

  • [Presentation] IgE依存性即時型反応の関与が示唆された新生児乳児消化管アレルギーの超低出生体重児例2017

    • Author(s)
      奥野貴士
    • Organizer
      第62回日本新生児成育医学会
    • Related Report
      2017 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi