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Effectiveness of interventions to improve social function in patient with brain injury.

Research Project

Project/Area Number 15K19722
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionKyoto University

Principal Investigator

UBUKATA SHIHO  京都大学, 医学研究科, 研究員 (40738960)

Research Collaborator UEDA Keita  京都大学, 大学院医学研究科脳病態生理学講座, 助教 (60573079)
SUGIHARA Genichi  京都大学, 大学院医学研究科脳病態生理学講座, 院内講師 (70402261)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords高次脳機能障害 / 外傷性脳損傷 / 認知リハビリテーション / 社会認知 / 社会機能 / 神経画像 / コネクトーム / SCIT / 心の理論 / 表情認知 / 社会的認知 / リハビリテーション / 生活習慣 / MRI
Outline of Final Research Achievements

To determine the effectiveness of interventions addressing cognitive impairments to improve social function in patients with brain injury. 1) Neuroimaging analyses revealed that patients exhibited volume reductions in connectivity via the corpus callosum, however, most of the cortical grey matter volume were intact.2)Impairments in cognitive processing speed and theory of mind were the best predictors of social function. 3)Through the group treatment using "Social Cognition and Interaction Training", ability of judging facial expressions of others was improved in patient with brain injury. These results suggested that focused rehabilitation approach might be useful to improve social function. Furthermore, neuroimaging method would give us biological evidence to select an optimal intervention.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (12 results)

All 2017 2016 2015

All Journal Article (4 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 3 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Int'l Joint Research: 5 results) Book (1 results)

  • [Journal Article] Facial emotion recognition in patients with focal and diffuse axonal injury.2017

    • Author(s)
      Yassin W, Callahan B, Sugihara G, Ubukata S, Murai T, Ueda K
    • Journal Title

      Brain Injury

      Volume: - Pages: 1-7

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 社会的認知障害を呈した高次脳機能障害患者に対するSCITを用いたグループ治療―予備的研究―2016

    • Author(s)
      塚越千尋, 俵あゆみ, 松岡慧, 生方志浦, 納谷敦夫
    • Journal Title

      高次脳機能研究

      Volume: - Pages: 450-458

    • NAID

      130006140531

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] 高次脳機能障害における社会的行動障害への対応2016

    • Author(s)
      村井俊哉, 生方志浦
    • Journal Title

      日本医師会雑誌

      Volume: - Pages: 1211-1214

    • Related Report
      2016 Research-status Report
  • [Journal Article] Corpus Callosum Pathology as a Potential Surrogate Marker of Cognitive Impairment in Diffuse Axonal Injury.2015

    • Author(s)
      Ubukata S, Ueda K, Sugihara G, Yassin W, Aso T, Fukuyama H, Murai T.
    • Journal Title

      J Neuropsychiatry Clin Neurosci.

      Volume: 28 Issue: 2 Pages: 97-103

    • DOI

      10.1176/appi.neuropsych.15070159

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Predictor of social function and quality of life in patient with traumatic brain injury2017

    • Author(s)
      Ubukata S, Sugihara G, Murai T, Ueda K.
    • Organizer
      25th European Congress of Psychiatry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] White matter disruption may not cause grey matter alteration in patients with diffuse axonal injury2017

    • Author(s)
      Ubukata S, Oishi N, Sugihara G, Fujimoto G, Aso T, Fukuyama H, Murai T, Ueda K.
    • Organizer
      The 41st annual Meeting of the Japan Neuroscience Society
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural basis of cognitive impairments in patients with diffuse axonal injury.2016

    • Author(s)
      Ubukata S, Oishi N, Sugihara G, Yassin W, Aso T, Fukuyama H, Murai T, Ueda K
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2016-11-12
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Structural connectivity and cognitive Impairment in patients with diffuse axonal injury2016

    • Author(s)
      Ubukata S, Oishi N, Sugihara G, Yassin W, Aso T, Fukuyama H, Murai T, Ueda K
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Related Report
      2016 Research-status Report
  • [Presentation] Abnormal corpus callosum connectivity in patients with diffuse axonal injury2016

    • Author(s)
      Ubukata S, Oishi N, Sugihara G, Yassin W, Aso T, Fukuyama H, Murai T, Ueda K
    • Organizer
      the 22nd Organizetion for Human Brain Mapping
    • Place of Presentation
      ジュネーブ
    • Year and Date
      2016-06-26
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 外傷性脳損傷後の社会機能に関連する認知機能障害の検討2015

    • Author(s)
      生方志浦、上田敬太、杉原玄一、村井俊哉
    • Organizer
      作業療法神経科学研究会
    • Place of Presentation
      札幌(北海道)
    • Year and Date
      2015-07-25
    • Related Report
      2015 Research-status Report
  • [Presentation] Neural basis of cognitive impairments in patients with diffuse axonal injury.2015

    • Author(s)
      Ubukata S, Ueda K, Sugihara G, Yassin W, Aso T, Fukuyama H and Murai T.
    • Organizer
      Organization for Human Brain Mapping 2015
    • Place of Presentation
      Honolulu (Hawai)
    • Year and Date
      2015-06-15
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Book] 高次脳機能障害の考えかたと画像診断2016

    • Author(s)
      村井俊哉, 生方志浦
    • Total Pages
      8
    • Publisher
      中外医学社
    • Related Report
      2016 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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