Elucidation of neural mechanisms in antidepressant and cognitive behavioral therapy for chronic pain
| Project/Area Number |
15K19730
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
Yoshino Atsuo 広島大学, 医歯薬保健学研究科(医), 特任助教 (90633727)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 慢性疼痛 / 認知行動療法 / fMRI / 抗うつ薬治療 |
|---|
| Outline of Final Research Achievements |
We conducted cognitive behavioral therapy (CBT) or antidepressant treatment for chronic pain, and examined pain ratings, psychological ratings, and a neuroimaging method (fMRI) at pretreatment and post-treatment. Our outcomes were as follows: 1) the neural changes of the orbitofrontal cortex, inferior parietal lobule, and paracentral lobule by CBT (Yoshino et al., 2018) and 2) the different resting-state neural activities of the dorsolateral prefrontal cortex and thalamus from depressive patients and healthy controls (Yoshino et al., 2017). We clarified a pathological mechanism of chronic pain and a neural change by treatment.
|
Report
(4 results)
Research Products
(16 results)
-
-
-
-
-
-
-
-
-
[Journal Article] Effectiveness of group cognitive behavioral therapy for somatoform pain disorder patients in Japan: A preliminary non-case-control study2015
Author(s)
Atsuo Yoshino, Yasumasa Okamoto, Mitsuru Doi, Masaru Horikoshi, Kyoko Oshita, Ryuji Nakamura, Naofumi Otsuru, Shinpei Yoshimura, Keisuke Tanaka, Koki Takagaki, Ran Jinnin, Hidehisa Yamashita, Masashi Kawamoto MD and Shigeto Yamawaki
-
Journal Title
Psychiatry and Clinical Neurosciences
Volume: 69
Issue: 12
Pages: 763-772
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
-
-
-
-
-
-
-
