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Does light therapy induce neurogenesis?: FDG-PET stady

Research Project

Project/Area Number 15K19737
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionOita University

Principal Investigator

KOHNO Kentaro  大分大学, 医学部, 客員研究員 (30555181)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords高照度光療法 / 神経新生 / FDG-PET
Outline of Final Research Achievements

In the present study, not only FDG-PET but also MRI were used to measure morphological changes as well as metabolic changes to determine neurogenesis. Subjects were randomly assigned to blight light therapy and dim light therapy, both of which continued for 4 weeks. As a result, blight light therapy but not dim light therapy significantly increased volume and glucose uptake in the right olfactory bulb. The present findings suggest that bright light therapy for 4 weeks may induce neurogenesis in the right olfactory bulb.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results) (of which Invited: 1 results)

  • [Journal Article] Postcomparison of [18F]-fluorodeoxyglucose uptake in the brain after short-term bright light exposure and no intervention2016

    • Author(s)
      Kohno K, Terao T, Hatano K, Kodama K, Makino M, Mizokami Y, Kamei K, Sakai A, Shirahama M, Hirakawa H, Kashino G, Matsumoto S, Mori H, Ohashi K, Yano T
    • Journal Title

      Acta Psychiatr Scand

      Volume: 134 Issue: 1 Pages: 65-72

    • DOI

      10.1111/acps.12569

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 双極性障害と光の影響2016

    • Author(s)
      河野 健太郎
    • Organizer
      第26回日本臨床精神神経薬理学会
    • Place of Presentation
      ホルトホール大分(大分県・大分市)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高照度光療法と脳画像研究2016

    • Author(s)
      平川 博文
    • Organizer
      第26回日本臨床精神神経薬理学会
    • Place of Presentation
      ホルトホール大分(大分県・大分市)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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