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The role of hypothalamic preoptic calcitonin-receptor neurons in parental behavior

Research Project

Project/Area Number 15K19755
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

Tokita Kenichi  国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 (70384188)

Research Collaborator KURODA Kumi  
MIYAMICHI Kazunari  
YOSHIHARA Chihiro  
SHINOZUKA Kazutaka  
OHNISHI Ryuko  
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords養育行動 / 内側視索前野 / カルシトニンレセプター / マウス / 神経解剖学
Outline of Final Research Achievements

In the present study, the function of calcitonin receptor in the medial preoptic area in parental behavior was investigated in female mice using neuroanatomical and behavioral approaches. Afferent and efferent connections of calcitonin receptor neurons in the medial preoptic area were analyzed. Both calcitonin receptor-neuron specific loss of function and supression of calcitonin receptor expression lowered the quality of parental behavior in female mice.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (2 results)

All 2016

All Presentation (2 results)

  • [Presentation] Neural circuits controlling pup-directed behaviors in male mice2016

    • Author(s)
      時田賢一
    • Organizer
      ISOT2016 17th International Symposium on Olfaction and Taste
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] Neural circuits involved in paternal and infanticidal behavior in mice2016

    • Author(s)
      時田賢一
    • Organizer
      第 39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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