The role of hypothalamic preoptic calcitonin-receptor neurons in parental behavior
| Project/Area Number |
15K19755
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
Tokita Kenichi 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 (70384188)
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| Research Collaborator |
KURODA Kumi
MIYAMICHI Kazunari
YOSHIHARA Chihiro
SHINOZUKA Kazutaka
OHNISHI Ryuko
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 養育行動 / 内側視索前野 / カルシトニンレセプター / マウス / 神経解剖学 |
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| Outline of Final Research Achievements |
In the present study, the function of calcitonin receptor in the medial preoptic area in parental behavior was investigated in female mice using neuroanatomical and behavioral approaches. Afferent and efferent connections of calcitonin receptor neurons in the medial preoptic area were analyzed. Both calcitonin receptor-neuron specific loss of function and supression of calcitonin receptor expression lowered the quality of parental behavior in female mice.
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Report
(3 results)
Research Products
(2 results)
