Basic study of the sensitization effect on proton beam therapy of hyperthermia

Research Project

Project/Area Number	15K19768
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Radiation science
Research Institution	University of Tsukuba
Principal Investigator	Saito Takahi 筑波大学, 附属病院, 医員 (70750107)
Research Collaborator	Fukumitsu Nobuyoshi 筑波大学附属病院, 放射線腫瘍科, 准教授 (40277075)
Project Period (FY)	2015-04-01 – 2017-03-31
Project Status	Completed (Fiscal Year 2016)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	陽子線治療 / 温熱療法 / 化学療法
Outline of Final Research Achievements	Although proton beam therapy has excellent dose concentration, there are still radiation resistant cancers. Hyperthermia is one of the therapies that provide sensitization of radiotherapy using X-rays. But We don't know what kind of sensitization will be produced biologically when hyperthermia is combined with proton beam therapy. Fundamental experiment will be conducted to establish biological data that will be a breakthrough to refractory cancer therapy showing radiation resistance.

Report

(3 results)